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上海药物研究所 [45]
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Comparative Analysis of the Composition of Fatty Acids and Metabolites between Black Tibetan and Chaka Sheep on the Qinghai-Tibet Plateau
期刊论文
ANIMALS, 2022, 卷号: 12, 期号: 20
作者:
Guo, TQ
;
Wang, XG
;
Zhang, Q
;
Wei, L
;
Liu, HJ
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/02
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
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  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Alteration of the PKA-CREB cascade in the mPFC accompanying prepulse inhibition deficits: evidence from adolescent social isolation and chronic SKF38393 injection during early adolescence
期刊论文
BEHAVIOURAL PHARMACOLOGY, 2021, 卷号: 32, 期号: 6, 页码: 487-496
作者:
Du, Wei
;
Li, Man
;
Zhou, Hao
;
Shao, Feng
;
Wang, Weiwen
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  |  
浏览/下载:44/0
  |  
提交时间:2021/09/24
adolescent social isolation
cAMP-dependent protein kinase A
cAMP-response element-binding protein
medial prefrontal cortex
prepulse inhibition
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8
作者:
Wang, Xi
;
Cheng, Xi
;
Zhao, Lihua
;
Wang, Yuzhe
;
Ye, Chenyu
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  |  
浏览/下载:25/0
  |  
提交时间:2021/11/04
parathyroid hormone receptor 2
cryo-electron microscopy
G protein-coupled receptor
ligand recognition
syndromic short stature
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:
Zhou, Qingtong
;
Guo, Wanjing
;
Dai, Antao
;
Cai, Xiaoqing
;
Vass, Marton
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  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
GLP-1R
virtual screening
allosteric modulator
drug discovery
molecular docking
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:
Darbalaei, Sanaz
;
Yuliantie, Elita
;
Dai, Antao
;
Chang, Rulue
;
Zhao, Peishen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
G protein-coupled receptor
Glucagon-like peptide-1 receptor
Glucagon receptor
Biased agonism
Unimolecular dual agonist
Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 1-10
作者:
Ji, Xiaoya
;
Li, Na
;
Ma, Mei
;
Rao, Kaifeng
;
Yang, Rong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/09/15
Tricresyl phosphate isomers
Estrogenic effect
GPER
cAMP
Calcium mobilization
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
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