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Opportunities and challenges of fucoidan for tumors therapy
期刊论文
CARBOHYDRATE POLYMERS, 2024, 卷号: 324, 页码: 13
作者:
Yu, Haoyu
;
Zhang, Quanbin
;
Farooqi, Ammad Ahmad
;
Wang, Jing
;
Yue, Yang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/04/07
Brown algae
Fucoidan
Structure
Anti-tumor
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Synthesis and biological evaluation of novel cabazitaxel analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 41, 页码: 12
作者:
Ren, Sumei
;
Zhang, Minmin
;
Wang, Yujie
;
Guo, Jia
;
Wang, Junfei
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
Tritium extraction
Hydrogen isotopes
Eutectic Pb-Li
Fusion fuel cycle
Cabazitaxel
Docetaxel
Taxel
Anticancer
Semi-synthesis
10-Deacetylbaccatin III
Cytotoxicity
A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma
期刊论文
BMC Cancer, 2021, 卷号: 21, 期号: 1
作者:
Cui,Jiujie
;
Yang,Haiyan
;
Liu,Jue
;
Chen,Donghui
;
Hu,Jiong
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/06/15
Pancreatic ductal adenocarcinoma
Phase I study
Safety
K-001
Clinical trial
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
;
Long, Xiubing
;
Jiang, Kailong
;
Song, Pinrao
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/06/11
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
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