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Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载:17/0  |  提交时间:2021/12/16
Design and synthesis of new lenalidomide analogs via Suzuki cross-coupling reaction 期刊论文
ARCHIV DER PHARMAZIE, 2020, 页码: 10
作者:  Xiao, Donghuai;  Wang, Yu-jie;  Wang, Han-lin;  Zhou, Yu-bo;  Li, Jia
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:  Wang, Jubo;  Li, Tinghan;  Zhao, Tengteng;  Wu, Tizhi;  Liu, Chuang
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models 期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:  Long, Fei;  He, Ye;  Fu, Haoyu;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 3, 页码: 760-776
作者:  Ding, Chunyong;  Tian, Qianting;  Li, Jie;  Jiao, Mingkun;  Song, Shanshan
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Design, synthesis, and anticancer properties of isocorydine derivatives 期刊论文
Bioorganic and Medicinal Chemistry, 2017, 卷号: 25, 期号: 24, 页码: 6542-6553
作者:  Yan, Qian;  Di DL(邸多隆);  Li, Wenguang;  Liu JX(柳军玺);  Zhang YX(张燕霞)
收藏  |  浏览/下载:25/0  |  提交时间:2018/06/20
Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5399-5402
作者:  Han, Mei;  Wang, Chengyan;  Ji, Yinchun;  Song, Zilan;  Xing, Li
收藏  |  浏览/下载:66/0  |  提交时间:2019/01/08
Dietary apigenin potentiates the inhibitory effect of interferon-alpha on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation 期刊论文
FOOD & NUTRITION RESEARCH, 2016, 卷号: 60, 页码: 31288(1-12)
作者:  He, YJ;  Yang, LJ;  Li, S;  Wang, F (reprint author), Chinese Acad Sci, Chengdu Inst Biol, 9 Sect 4 Renmin South Rd, Chengdu 610041, Peoples R China.;  Wang, F
收藏  |  浏览/下载:20/0  |  提交时间:2017/11/09
Discovery of phenylpiperazine derivatives as IGF-1R inhibitor with potent antiproliferative properties in vitro 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 5, 页码: 1067-1071
作者:  Guo, Feng-Jiao;  Sun, Juan;  Gao, Li-Li;  Wang, Xin-Yi;  Zhang, Yang
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/17


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