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Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106
作者:
Kong, Deyu
;
Xue, Tao
;
Guo, Bin
;
Cheng, Jianjun
;
Liu, Shunyin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Bioassay based screening for the antiplatelet aggregation quality markers of Polygonum multiflorum with UPLC and chemometrics
期刊论文
2019, 卷号: 166, 页码: 264-272
作者:
Li, Chunyu[1,2]
;
Tu, Can[3]
;
Che, Yi[4]
;
Zhang, Mingyu[1,2]
;
Dong, Bin[1,2]
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/06
Oral administration of leeches (Shuizhi): A review of the mechanisms of action on antiplatelet aggregation
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 103-109
作者:
Jiang Qiu
;
Wang Lingna
;
Hu Jinghong
;
Zhang Yongqing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Leeches
Platelet aggregation
Cardiovascular diseases (CVDs)
Mechanism
Oral administration
Bioassay based screening for the antiplatelet aggregation quality markers of Polygonum multiflorum with UPLC and chemometrics
期刊论文
2019, 卷号: 166, 页码: 264-272
作者:
Li, Chunyu
;
Tu, Can
;
Che, Yi
;
Zhang, Mingyu
;
Dong, Bin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Polygonum multiflorum
Bioassay
Quality control method
Antiplatelet aggregation
Spectrum-effect relationships
UPLC
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:
Peng, Jingjing
;
Zhao, Lifen
;
Wang, Lanlan
;
Chen, Hui
;
Qiu, Yunguang
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
P2Y(1) receptor antagonist
2-(phenoxyaryl)-3-urea derivatives
Anti-Platelet
Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xiaojiao
;
Liu, Ca
;
Zhu, Xiaoxue
;
Wei, Haijing
;
Zhang, Hong
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  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
vicagrel
pharmacokinetics
pharmacodynamics
safety
clopidogrel
Phospholipase C gamma 2 Signaling Cascade Contribute to the Antiplatelet Effect of Notoginsenoside Fc
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Ma, Wuren
;
Song, Xiaoping
;
Fan, Yunpeng
;
Cui, Li
;
Liu, Yingqiu
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Panax notoginseng
Notoginsenoside Fc
platelet aggregation
antiplatelet effect
thrombosis
phospholipase C gamma 2
Application of Feedback System Control Optimization Technique in Combined Use of Dual Antiplatelet Therapy and Herbal Medicines
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:
Liu, Wang
;
Li, Yu-Long
;
Feng, Mu-Ting
;
Zhao, Yu-Wei
;
Ding, Xianting
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
feedback systemcontrol
dual antiplatelet therapy
herbal medicine
platelet aggregation
optimization
synergism
Randomized Comparisons of Double-Dose Clopidogrel or Adjunctive Cilostazol Versus Standard Dual Antiplatelet in Patients With High Posttreatment Platelet Reactivity Results of the CREATIVE Trial
期刊论文
2018, 卷号: 137, 期号: 21, 页码: 2231-2245
作者:
Tang, Yi-Da
;
Wang, Wenyao
;
Yang, Min
;
Zhang, Kuo
;
Chen, Jing
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
cilostazol
clopidogrel
percutaneous coronary intervention
platelet aggregation inhibitors
platelet function test
Comparison on Anticoagulation and Antiplatelet Aggregation Effects of Puerarin with Heparin Sodium and Tirofiban Hydrochloride: An In Vitro Study
期刊论文
2018, 卷号: 24, 期号: 2, 页码: 103-108
作者:
Li Si-wei
;
Feng Xue
;
Xu Hao
;
Chen Ke-ji
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
puerarin
heparin
tirofiban hydrochloride
in vitro
Sonoclot coagulation analyzer
anticoagulation
antiplatelet aggregation
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