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中国医学科学院 北京... [7]
上海药物研究所 [5]
厦门大学 [3]
复旦大学上海医学院 [3]
合肥物质科学研究院 [3]
清华大学 [1]
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期刊论文 [24]
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The deep learning model combining CT image and clinicopathological information for predicting ALK fusion status and response to ALK-TKI therapy in non-small cell lung cancer patients
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020
作者:
Song, Zhengbo
;
Liu, Tianchi
;
Shi, Lei
;
Yu, Zongyang
;
Shen, Qing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/10/26
Deep learning model
Anaplastic lymphoma kinase
Computed tomography
Non-small cell lung cancer
Evaluating Solid Lung Adenocarcinoma Anaplastic Lymphoma Kinase Gene Rearrangement Using Noninvasive Radiomics Biomarkers
期刊论文
ONCOTARGETS AND THERAPY, 2020, 卷号: 13
作者:
Ma, De-Ning
;
Gao, Xin-Yi
;
Dan, Yi-Bo
;
Zhang, An-Ni
;
Wang, Wei-Jun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/11/26
radiogenomics
SVM
non-small cell lung cancer
anaplastic lymphoma kinase
epidermal growth factor receptor
Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397
作者:
Geng, Kaijun
;
Xia, Zongjun
;
Ji, Yinchun
;
Zhang, Ruisi (Ruthy)
;
Sun, Deqiao
收藏
  |  
浏览/下载:155/0
  |  
提交时间:2019/01/08
ALK
G1202R mutant
Drug resistance
2,4-Diarylaminopyrimidine
Resorcinol
Expression of anaplastic lymphoma kinase fusion gene in patients with lung sarcomatoid carcinoma and treatment analysis
期刊论文
2018, 卷号: 98, 期号: 9, 页码: 688-691
作者:
Niu H T
;
Dong P
;
Wang J N
;
Zeng Y X
;
Yuan W
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Anaplastic lymphoma kinase
Crizotinib
Fusion gene
Lung sarcomatoid carcinoma
Ventana immunohistochemistry assay for anaplastic lymphoma kinase gene rearrangement detection in patients with non-small cell lung cancer: A meta-analysis
期刊论文
THORACIC CANCER, 2017, 卷号: 8, 期号: 5, 页码: 471-476
作者:
Wang Zhiwei[1]
;
Jiang Yuan[2]
;
Yao Yihui[3]
;
Hou Xin[4]
;
Chen Jingtao[5]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/23
Anaplastic lymphoma kinase gene
meta-analysis
non-small cell lung cancer
Ventana immunohistochemistry assay
The diagnostic and follow-up role of radiological examination in advanced lung adenocarcinoma with anaplastic lymphoma kinase gene rearrangement
期刊论文
2017, 卷号: 10, 期号: 8, 页码: 12782-12789
作者:
Zhang, Li
;
Wu, Ning
;
Li, Meng
;
Ying, Jianming
;
Ouyang, Han
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
Adenocarcinoma of lung
anaplastic lymphoma kinase
diagnosis
follow-up
radiology
Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5399-5402
作者:
Han, Mei
;
Wang, Chengyan
;
Ji, Yinchun
;
Song, Zilan
;
Xing, Li
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
EML4-ALK kinase
Oxidative metabolism
Benzo[b]carbazolone
hERG
Antitumor activity
Aberrant Expression of Anaplastic Lymphoma Kinase in Ovarian Carcinoma Independent of Gene Rearrangement
期刊论文
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2016, 卷号: 35, 期号: 4
作者:
Tang, Shaoxian
;
Yang, Fei
;
Du, Xiang
;
Lu, Yongming
;
Zhang, Ling
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/13
ALK overexpression
Gene rearrangement
Ovarian high-grade serous carcinoma
Targeted therapy
Concordance of immunohistochemistry and fluorescent in situ hybridization for anaplastic lymphoma kinase (ALK) rearrangement in non-small cell lung cancer: results from a multicenter study in China
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 卷号: 9, 期号: 2
作者:
Sun, Yu
;
Yang, Fei
;
Zhou, Xiao-Yan
;
Zhou, Li-Xin
;
Li, Xiang-Hong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/06
Non-small cell lung cancer
EML4-ALK gene fusion
immunohistochemistry
fluorescent in situ hybridization
Concordance of immunohistochemistry and fluorescent in situ hybridization for anaplastic lymphoma kinase (ALK) rearrangement in non-small cell lung cancer: results from a multicenter study in China
期刊论文
2016, 卷号: 9, 期号: 2, 页码: 2642-2653
作者:
Sun, Yu
;
Yang, Fei
;
Zhou, Xiao-Yan
;
Zhou, Li-Xin
;
Li, Xiang-Hong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Non-small cell lung cancer
EML4-ALK gene fusion
immunohistochemistry
fluorescent in situ hybridization
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