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上海药物研究所 [12]
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复旦大学上海医学院 [6]
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期刊论文 [64]
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DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Yeast-Based A beta 1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
期刊论文
VACCINES, 2020, 卷号: 8, 期号: 3, 页码: 13
作者:
Liu, Dong-qun
;
Lu, Shuai
;
Zhang, Lun
;
Huang, Ya-ru
;
Ji, Mei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/03/29
Alzheimer's disease
beta-amyloid
active immunotherapy
yeast
vaccine
Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid-beta had distinct effects on neuropathology and cognitive deficits in EAE/AD mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 页码: 12
作者:
Yu, Xiao-Lin
;
Zhu, Jie
;
Liu, Xiang-meng
;
Xu, Peng-xin
;
Zhang, Yue
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/05/21
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Effects of BIS-MEP on Reversing Amyloid Plaque Deposition and Spatial Learning and Memory Impairments in a Mouse Model of beta-Amyloid Peptide- and Ibotenic Acid-Induced Alzheimer's Disease
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2019, 卷号: 11
作者:
Wang, Yu
;
Xia, Jia
;
Shen, Mengjun
;
Zhou, Yifan
;
Wu, Zhe
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Alzheimer's disease
acetylcholinesterase inhibitor
BIS-MEP
beta-amyloid peptide
learning
memory
Anti-diabetic vanadyl complexes reduced Alzheimer’s disease pathology independent of amyloid plaque deposition
期刊论文
Science China Life Sciences, 2019, 卷号: Vol.62 No.1, 页码: 126-139
作者:
Yaqiong Dong
;
Tessandra Stewart
;
Yue Zhang
;
Min Shi
;
Chang Tan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
Alzheimer’s
disease
vanadyl
(IV)
acetylacetonate
neuroprotection
Aβ
oligomerization
PPARγ-AMPK
Grp75
Engineered Bacillus subtilis biofilms as living glues
期刊论文
MATERIALS TODAY, 2019, 卷号: 28, 页码: 40-48
作者:
Zhang, C
;
Huang, JF
;
Zhang, JC
;
Liu, SY
;
Cui, MK
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/10/16
MUSSEL FOOT PROTEINS
UNDERWATER ADHESIVE
SURFACE
COACERVATION
CHEMISTRY
STICKING
FIBERS
PLAQUE
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
Early A beta-HBc virus-like particles immunization had better effects on preventing the deficit of learning and memory abilities and reducing cerebral A beta load in PDAPP mice
期刊论文
VACCINE, 2018, 卷号: 36, 页码: 5258-5264
作者:
Feng, Gaifeng
;
Zheng, Caifeng
;
Hui, Jianjun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
beta-amyloid peptide (A beta)
Amyloid plaque
Virus-like particles (VLPs)
Alzheimer's disease
Immunotherapy
Early Candidate Urine Biomarkers for Detecting Alzheimer's Disease Before Amyloid-beta Plaque Deposition in an APP (swe)/PSEN1(dE9) Transgenic Mouse Model
期刊论文
2018, 卷号: 66, 期号: 2, 页码: 613-637
作者:
Zhang, Fanshuang
;
Wei, Jing
;
Li, Xundou
;
Ma, Chao
;
Gao, Youhe
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Alzheimer's disease
APP (swe)/PSEN1(dE9)
early diagnosis
urine proteome
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