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上海药物研究所 [9]
北京大学 [2]
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西北高原生物研究所 [1]
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期刊论文 [18]
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Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 8, 页码: 4392-4399
作者:
Shen, Wei
;
Wang, Qiu-Wen
;
Liu, Yao-Nan
;
Marchetto, Maria C.
;
Linker, Sara
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  |  
浏览/下载:44/0
  |  
提交时间:2020/04/06
synaptotagmin-7
induced pluripotent stem cell
mental disorder
bipolar disorder
Enhancement of cisplatin efficacy by lipid-CaO2 nanocarrier-mediated comprehensive modulation of the tumor microenvironment
期刊论文
BIOMATERIALS SCIENCE, 2019, 卷号: 7, 期号: 10, 页码: 4260-4272
作者:
He, Chuanchuan
;
Zhang, Xiaojuan
;
Yan, Ruicong
;
Zhao, Pengxuan
;
Chen, Yan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 9, 页码: 10089-10103
作者:
Liu, Ge
;
Kuang, Shan
;
Cao, Ruobing
;
Wang, Ju
;
Peng, Quancai
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/11/14
stearoyl CoA desaturase 1
monounsaturated FAs
ATP production
HgS Inhibits Oxidative Stress Caused by Hypoxia through Regulation of 5-HT Metabolism Pathway
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 6
作者:
He, Qiangqiang
;
Ma, Ji
;
Kalavagunta, Praveen Kumar
;
Zhou, Liangliang
;
Zhu, Junyi
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/11/26
hypoxia
reactive oxygen species
oxidative stress
5-Hydroxytryptamine
cinnabar
p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 26, 页码: 8344-8361
作者:
Peng, Jinjin
;
Li, Jiacheng
;
Huang, Jing
;
Xu, Pan
;
Huang, Heming
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
liver injury
inflammation
macrophages
epigenetics
acetyltransferase inhibitor
BDNF-GSK-3 beta-beta-Catenin Pathway in the mPFC Is Involved in Antidepressant-Like Effects of Morinda officinalis Oligosaccharides in Rats
期刊论文
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2017
Xu, Ling-Zhi
;
Xu, De-Feng
;
Han, Ying
;
Liu, Li-Jing
;
Sun, Cheng-Yu
;
Deng, Jia-Hui
;
Zhang, Ruo-Xi
;
Yuan, Ming
;
Zhang, Su-Zhen
;
Li, Zhi-Meng
;
Xu, Yi
;
Li, Jin-Sheng
;
Xie, Su-Hua
;
Li, Su-Xia
;
Zhang, Hong-Yan
;
Lu, Lin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/12/03
Morinda officinalis oligosaccharides
depression
GSK-3 beta, beta-catenin
BDNF
GLYCOGEN-SYNTHASE KINASE-3
RETRIEVAL-EXTINCTION PROCEDURE
MEDIAL PREFRONTAL CORTEX
NUCLEUS-ACCUMBENS CORE
CHRONIC MILD STRESS
BETA-CATENIN
BASOLATERAL AMYGDALA
DEPRESSED-PATIENTS
SIGNALING PATHWAY
PC12 CELLS
DNA Repair Genes ERCC1 and BRCA1 Expression in Non-Small Cell Lung Cancer Chemotherapy Drug Resistance
期刊论文
MEDICAL SCIENCE MONITOR, 2016, 卷号: 22, 页码: 1999-2005
作者:
Wang, Shuai
;
Liu, Feng
;
Zhu, Jingyan
;
Chen, Peng
;
Liu, Hongxing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
1-Naphthylamine
Abnormalities, Drug-Induced
Genes, BRCA1
Concealing cellular defects in pluripotent stem cells
期刊论文
TRENDS IN CELL BIOLOGY, 2013, 卷号: 23, 期号: 12, 页码: 587-592
作者:
Zhang, Weiqi
;
Qu, Jing
;
Suzuki, Keiichiro
;
Liu, Guang-Hui
;
Izpisua Belmonte, Juan Carlos
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
pluripotent stem cell
reprogramming
disease modeling
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