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上海药物研究所 [45]
北京大学 [11]
厦门大学 [10]
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昆明植物研究所 [6]
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期刊论文 [154]
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Controlling the Shrinkage of 3D Hot Spot Droplets as a Microreactor for Quantitative SERS Detection of Anticancer Drugs in Serum Using a Handheld Raman Spectrometer
期刊论文
ANALYTICAL CHEMISTRY, 2022, 卷号: 94
作者:
Zhou, Guoliang
;
Li, Pan
;
Ge, Meihong
;
Wang, Junping
;
Chen, Siyu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/05/16
Ginsenoside Rh2 Induces HeLa Apoptosis through Upregulating Endoplasmic Reticulum Stress-Related and Downstream Apoptotic Gene Expression
期刊论文
Molecules, 2022, 卷号: 27, 期号: 22, 页码: 15
作者:
Y. Liu
;
X. R. Wang
;
J. H. Qiao
;
J. W. Wang
;
L. L. Jiang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/06/14
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:
Wu, Qian
;
Chen, Dan-Qi
;
Sun, Lin
;
Huan, Xia-Juan
;
Bao, Xu-Bin
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2021/05/24
N2817
Bivalent BET inhibitors
Monovalent BET inhibitors
TAF1
Anticancer activity
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy
期刊论文
ADVANCED MATERIALS, 2021, 页码: 12
作者:
Ding, Jingjing
;
Lu, Guihong
;
Nie, Weidong
;
Huang, Li-Li
;
Zhang, Yahui
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/03/29
chemotherapy
extracellular vesicle
immunotherapy
photodynamic therapy
tumor microenvironment
MicroRNA-16-5p regulates cell survival, cell cycle and apoptosis by targetingAKT3in prostate cancer cells
期刊论文
ONCOLOGY REPORTS, 2020, 卷号: 44, 期号: 3, 页码: 1282-1292
作者:
Wang, Fang
;
Wang, Wendi
;
Lu, Lina
;
Xie, Yi
;
Yan, Junfang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/15
microRNA-16-5p
cell survival
cell cycle
apoptosis
prostate cancer
Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Yu, De-Hua
;
Xu, Zhi-Yuan
;
Mo, Shaowei
;
Yuan, Li
;
Cheng, Xiang-Dong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/10/26
MDMX
MDM2
p53
oncogene
tumor suppressor
inhibitors
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
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