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浏览/检索结果: 共2条，第1-2条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Efficient in vivo gene editing using ribonucleoproteins in skin stem cells of recessive dystrophic epidermolysis bullosa mouse model 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017 Wu, Wenbo; Lu, Zhiwei; Li, Fei; Wang, Wenjie; Qian, Nannan; Duan, Jinzhi; Zhang, Yu; Wang, Fengchao; Chen, Ting 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 in vivo gene editing  Cas9/sgRNA ribonucleoproteins  skin stem cell  electroporation  RDEB  BASEMENT-MEMBRANE ZONE  VII COLLAGEN  ANCHORING FIBRILS  MUSCULAR-DYSTROPHY  INJECTION  THERAPY  MUSCLE  FIBROBLASTS  EXPRESSION  CORRECTS   V-shaped electro-optic characteristics in FLC gels (EI CONFERENCE) 会议论文 Li J.; Zhu X.; Xuan L.; Huang X. 收藏  |  浏览/下载：26/0  |  提交时间：2013/03/25 The effects of polymer network formed under UV irradiation with electric field application ( 50V  5Hz) to ferroelectric liquid crystal (FLC) molecules orientation and electrooptic characteristics have been studied. The polymer network formed in SmC*phase is anisotropic and fibrils-like  and a typical striped texture was observed in the cell. The FLC gels exhibit a symmetric V-shaped electrooptic characteristics with thresholdless voltage and high contrast ratio (40:1). A theory explanation of the unique properties is given by establishing a molecular orientation model and conducting a computer simulation. A good fitting of the electrooptic dynamic response of FLC gels has been obtained by introducing a potential (bulk anchoring energy) originated from the photo-cured polymer network. 2002 Taylor Francis.