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Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:  Guo, Huihui;  Zhang, Xilin;  Xie, Shangzhi;  Chen, Tianwei;  Xie, Dong
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/22
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
收藏  |  浏览/下载:76/0  |  提交时间:2022/02/14
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载:39/0  |  提交时间:2022/01/04
Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis 期刊论文
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 12
作者:  Liao, Min;  Dong, Qiongye;  Chen, Ruiqing;  Xu, Liqian;  Jiang, Yuxuan
收藏  |  浏览/下载:33/0  |  提交时间:2021/12/01
Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing 期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:  Mao, Rui;  Zhang, Xiaoyun;  Kong, Youyong;  Wu, Shanshan;  Huo, Hai-qin
收藏  |  浏览/下载:34/0  |  提交时间:2021/08/17
Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 8
作者:  Zhu, Yun-ting;  Zhang, Yi-fan;  Jiang, Jin-fang;  Yang, Yong;  Guo, Li-xia
收藏  |  浏览/下载:27/0  |  提交时间:2021/05/24
A Versatile Transcription-Translation in One Approach for Activation of Cryptic Biosynthetic Gene Clusters 期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 9, 页码: 2551-2557
作者:  Zhang, Qian;  Ren, Jin-Wei;  Wang, Weishan;  Zhai, Ji'an;  Yang, Jing
收藏  |  浏览/下载:17/0  |  提交时间:2020/12/17
Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer 期刊论文
CANCER CELL, 2020, 卷号: 38, 期号: 1, 页码: 115-+
作者:  Tang, Yang;  Fang, Gemin;  Guo, Fenghua;  Zhang, Hui;  Chen, Xiaoxu
收藏  |  浏览/下载:93/0  |  提交时间:2020/12/24
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/01
PD-L1 expression and T cells infiltration in patients with uncommon EGFR-mutant non-small cell lung cancer and the response to immunotherapy 期刊论文
LUNG CANCER, 2020, 卷号: 142
作者:  Chen, Kaiyan;  Cheng, Guoping;  Zhang, Fanrong;  Zhu, Guanxia;  Xu, Yanjun
收藏  |  浏览/下载:24/0  |  提交时间:2020/11/26


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