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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:
C Pergola
;
J Gerstmeier
;
B Monch
;
B Çaliskan
;
S Luderer
收藏
  |  
浏览/下载:224/0
  |  
提交时间:2017/07/24
Correlation of LOX-5 and COX-2 expression with inflammatory pathology and clinical features of adenomyosis
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 1
作者:
Chen, Li
;
Li, Caixia
;
Chen, Rong
;
Jiang, Caixia
;
Cheng, Zhongping
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
lipoxygenase-5
cyclooxygenase 2
adenomyosis
inflammatory pathology
menstruation
dysmenorrhea
Celecoxib aggravates atherogenesis and upregulates leukotrienes in ApoE mice and lipopolysaccharide-stimulated RAW264.7 macrophages
期刊论文
Atherosclerosis, 2019
作者:
Yimin Pang
;
Lu Gan
;
Xianzhe Wang
;
Qi Su
;
Cong Liang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/17
Atherosclerosis
COX-2-selective inhibitors
Cyclooxygenase-2
5-Lipoxygenase
Leukotrienes
ApoE-/- mice
RAW264.7 macrophages
5-Lipoxygenase Knockout Aggravated Apical Periodontitis in a Murine Model
期刊论文
JOURNAL OF DENTAL RESEARCH, 2018, 卷号: 97, 期号: 4
作者:
Wu, Y.
;
Sun, H.
;
Yang, B.
;
Liu, X.
;
Wang, J.
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
bacteria
bone loss
infectious disease
osteoclast
inflammation
host pathogen interactions
MiR-216a-3p inhibits colorectal cancer cell proliferation through direct targeting COX-2 and ALOX5
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 卷号: 119, 期号: 2, 页码: 1755-1766
作者:
Wang, Dongxia
;
Li, Yuechun
;
Zhang, Chun
;
Li, Xianming
;
Yu, Jinming
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
5-lipoxygenase (ALOX5) (5-LO)
cell proliferation
colorectal cancer
(CRC)
cyclooxygenase-2 (COX-2)
miR-216a-3p
Biocontrol of grapevine aerial and root pathogens by Paenibacillus sp strain B2 and paenimyxin in vitro and in planta
期刊论文
BIOLOGICAL CONTROL, 2017, 卷号: 109, 期号: 0, 页码: 42-50
作者:
Hao, Zhipeng
;
Van Tuinen, Diederik
;
Wipf, Daniel
;
Fayolle, Leon
;
Chataignier, Odile
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  |  
浏览/下载:17/0
  |  
提交时间:2018/07/20
Paenibacillus
Paenimyxin
Grapevine Pathogens
Biocontrol
Defence Related Genes
Evolution and Expansion of the Prokaryote-Like Lipoxygenase Family in the Brown Alga Saccharina japonica
期刊论文
FRONTIERS IN PLANT SCIENCE, 2017, 卷号: 8
作者:
Teng, Linhong[1]
;
Han, Wentao[2]
;
Fan, Xiao[3]
;
Xu, Dong[4]
;
Zhang, Xiaowen[5]
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  |  
浏览/下载:4/0
  |  
提交时间:2020/01/02
lipoxygenase
brown algae
gene duplication
selection pressure
functional divergence
12-Lipoxygenase Inhibition on Microalbuminuria in Type-1 and Type-2 Diabetes Is Associated with Changes of Glomerular Angiotensin II Type 1 Receptor Related to Insulin Resistance
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 5
作者:
Cheng, Yan-Li
;
Xu, Hong-Zhao
;
Wang, Wan-Ning
;
Wu, Hao
;
Zhang, Yuan-Yuan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
12-lipoxygenase
insulin resistance
angiotensin II type 1 receptor
diabetic nephropathy
Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016
Meng, Hu
;
McClendon, Christopher L.
;
Dai, Ziwei
;
Li, Kenan
;
Zhang, Xiaoling
;
He, Shan
;
Shang, Erchang
;
Liu, Ying
;
Lai, Luhua
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
INHIBITION
ENZYMES
MODEL
SITE
BIOSYNTHESIS
PROSTACYCLIN
PROTEINS
EFFECTOR
SYNTHASE
LIGANDS
5-Lipoxygenase ablation protects mice against acetaminophen-induced liver toxicity.
期刊论文
Br J Pharmacol., 2016, 卷号: Vol.173 No.1, 页码: 66-76
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  |  
浏览/下载:6/0
  |  
提交时间:2019/03/05
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