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南华大学 [1]
上海药物研究所 [1]
昆明植物研究所 [1]
武汉大学 [1]
复旦大学上海医学院 [1]
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期刊论文 [7]
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2018 [2]
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Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing[S]
期刊论文
JOURNAL OF LIPID RESEARCH, 2019, 卷号: 60, 期号: 10
作者:
Chen, Liang
;
Ma, Mei-Yan
;
Sun, Ming
;
Jiang, Lu-Yi
;
Zhao, Xue-Tong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
mevalonate
lanosterol
sterol intermediates
3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation
sterol regulatory element-binding protein-2 cleavage
clustered regularly interspaced short palindromic repeats (CRISPR)
CRISPR associated protein 9 (Cas9)
sterol regulatory element-binding protein-2
Phenolic Compounds from Belamcanda chinensis Seeds
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 580
作者:
Song, Ying-Ying
;
Liu, Ying
;
Yan, Yong-Ming
;
Lu, Xi-Feng
;
Cheng, Yong-Xian
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2018/07/02
Belamcanda Chinensis
Belamcanosides a And b
Gc Analysis
Hmgcr
Sqle
Ldlr
Sort1
Statin-naive anti-HMGCR antibody-mediated necrotizing myopathy in China
期刊论文
JOURNAL OF CLINICAL NEUROSCIENCE, 2018, 卷号: 57
作者:
Jiao, Yuqiong
;
Cai, Shuang
;
Lin, Jie
;
Zhu, Wenhua
;
Xi, Jianying
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)
Immune -mediated necrotizing myopathy
Statin-naive
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse nonalcoholic steatohepatitis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 5, 页码: 660-671
作者:
Liu, Ming-xia
;
Gao, Man
;
Li, Chun-zhu
;
Yu, Cun-zhi
;
Yan, Hong
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
non-alcoholic steatohepatitis
cholesterol accumulation
Dicer1
HMGCR
microRNA-29
MCD diet-treated mice
IDOL, inducible degrader of low-density lipoprotein receptor, serves as a potential therapeutic target for dyslipidemia
期刊论文
Medical Hypotheses, 2016, 卷号: 86, 期号: Volume 86, 页码: 138-142
作者:
Zhang, Cai-ping
;
Tian, Ying
;
Zhang, Min
;
Tuo, Qin-hui
;
Chen, Jian-xiong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
Non-HDL-C
non-high density lipoprotein cholesterol
LDL-C
low-density lipoprotein cholesterol
ASCVD
atherosclerotic cardiovascular disease
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reductase
SREBPs
sterol response element binding proteins
PCSK9
pro-protein convertase subtilisin/kexin type 9
IDOL
inducible degrader of LDLR
LXRs
liver X receptors
MYLIP
myosin regulatory light chain interacting protein
FERM
frame of ezrin/radixin/moesin homology
RING
really interesting new gene
PTB
phosphotyrosine-binding
MVB
multivesicular body
IDOL, inducible degrader of low-density lipoprotein receptor, serves as a potential therapeutic target for dyslipidemia
期刊论文
Medical Hypotheses, 2016, 卷号: 86, 期号: Volume 86, 页码: 138-142
作者:
Zhang, Cai-ping
;
Tian, Ying
;
Zhang, Min
;
Tuo, Qin-hui
;
Chen, Jian-xiong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
Non-HDL-C
non-high density lipoprotein cholesterol
LDL-C
low-density lipoprotein cholesterol
ASCVD
atherosclerotic cardiovascular disease
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reductase
SREBPs
sterol response element binding proteins
PCSK9
pro-protein convertase subtilisin/kexin type 9
IDOL
inducible degrader of LDLR
LXRs
liver X receptors
MYLIP
myosin regulatory light chain interacting protein
FERM
frame of ezrin/radixin/moesin homology
RING
really interesting new gene
PTB
phosphotyrosine-binding
MVB
multivesicular body
Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2010, 卷号: 42, 期号: 5, 页码: 303-310
作者:
Miao, HH
;
Jiang, W
;
Ge, LA
;
Li, BL
;
Song, BL
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2015/07/22
HMG-CoA reductase
endoplasmic reticulum associated protein degradation (ERAD)
tetraglutamic acid residue
gp78
UBE2G2
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