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科研机构
上海大学 [7]
中国水产科学院 [2]
内容类型
期刊论文 [9]
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2018 [1]
2017 [2]
2016 [2]
2015 [1]
2013 [2]
2012 [1]
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Bioactivation of 1-chloro-2-hydroxy-3-butene, an in vitro metabolite of 1,3-butadiene, by rat liver microsomes
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 卷号: 282, 页码: 36-44
作者:
Wang, Ye[1]
;
Yu, Ying-Xin[2]
;
Luan, Yang[3]
;
An, Jing[4]
;
Yin, Dong-Guang[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/22
Metabolism
Rat liver microsomes
1-chloro-2-hydroxy-3-butene
1-chloro-3
4-epoxy-2-butanol
1-chloro-3-buten-2-one
1
3-butadiene
Characterization of the Major Purine and Pyrimidine Adducts Formed after Incubations of 1-Chloro-3-buten-2-one with Single-/Double-Stranded DNA and Human Cells
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 页码: 552-563
作者:
Liu, Ling-Yan[1]
;
Zheng, Jin[2]
;
Kong, Cong[3]
;
An, Jing[4]
;
Yu, Ying-Xin[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/24
Characterization of the Major Purine and Pyrimidine Adducts Formed after Incubations of 1-Chloro-3-buten-2-one with Single-/Double-Stranded DNA and Human Cells
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 2, 页码: 552-563
作者:
Liu, Ling-Yan[1]
;
Zheng, Jin[2]
;
Kong, Cong[3]
;
An, Jing[4]
;
Yu, Ying-Xin[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/02
Identification of a Fused-Ring 2 '-Deoxyadenosine Adduct Formed in Human Cells Incubated with 1-Chloro-3-buten-2-one, a Potential Reactive Metabolite of 1,3-Butadiene
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 页码: 1041-1050
作者:
Zeng, Fang-Mao[1]
;
Liu, Lin-Yan[2]
;
Zheng, Jin[3]
;
Kong, Cong[4]
;
An, Jing[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/26
Identification of a Fused-Ring 2 '-Deoxyadenosine Adduct Formed in Human Cells Incubated with 1-Chloro-3-buten-2-one, a Potential Reactive Metabolite of 1,3-Butadiene
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 6, 页码: 1041-1050
作者:
Zeng, Fang-Mao[1]
;
Liu, Lin-Yan[2]
;
Zheng, Jin[3]
;
Kong, Cong[4]
;
An, Jing[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/02
Novel adducts from the reaction of 1-chloro-3-buten-2-one with 2 '-deoxyguanosine. Structural characterization and potential as tools to investigate 1,3-butadiene carcinogenicity
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2015, 卷号: 226, 页码: 40-48
作者:
Zheng, Jin[1]
;
Li, Yan[2]
;
Yu, Ying-Xin[3]
;
An, Jing[4]
;
Zhang, Xin-Yu[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/26
1
3-Butadiene
1-Chloro-3-buten-2-one
2′-Deoxyguanosine
Bioactivation
Biomarkers
DNA adducts
Cytotoxicity, genotoxicity, and mutagenicity of 1-chloro-2-hydroxy-3-butene and 1-chloro-3-buten-2-one, two alternative metabolites of 1,3-butadiene
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 271, 页码: 13-19
作者:
Liu, Xin-Jie[1]
;
Zeng, Fang-Mao[2]
;
An, Jing[3]
;
Yu, Ying-Xin[4]
;
Zhang, Xin-Yu[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/30
%Tail DNA
1
2
3
4-diepoxybutane
1
3-Butadiene
1
3-butadiene
1-Chloro-2-hydroxy-3-butene
1-Chloro-3-buten-2-one
1-chloro-2-hydroxy-3-butene
1-chloro-3-buten-2-one
3
4-epoxy-1
2-butanediol
3
4-epoxy-1-butene
3-(4
5-dimethyl-2-thiazolyl)-2
5-diphenyl-2H-tetrazolium bromide
ALS
BD
CBO
CHB
Comet assay
DEB
EB
EBD
FBS
GSH
Genotoxicity
MMS
MTT
Mutagenicity
RCE
SD
SSB
alkali-labile sites
fetal bovine serum
glutathione
methyl methanesulfonate
percentage of DNA in the tail
relative cloning efficiency
single-strand breaks
standard deviation
Formation of Fused-Ring 2 '-Deoxycytidine Adducts from 1-Chloro-3-buten-2-one, an in Vitro 1,3-Butadiene Metabolite, under in Vitro Physiological Conditions
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 卷号: 26, 页码: 1545-1553
作者:
Sun, Liang[1]
;
Pelah, Avishay[2]
;
Zhang, Dong-Ping[3]
;
Zhong, Yu-Fang[4]
;
An, Jing[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/04/30
Alcohol Dehydrogenase- and Rat Liver Cytosol-Dependent Bioactivation of 1-Chloro-2-hydroxy-3-butene to 1-Chloro-3-buten-2-one, a Bifunctional Alkylating Agent
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2012, 卷号: 25, 页码: 2600-2607
作者:
Elfarra, Adnan A.[1]
;
Zhang, Xin-Yu[2]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/30
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