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上海药物研究所 [15]
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期刊论文 [33]
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Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Insight of Synergistic Effect between CPP and Cargo on the Facilitation Mechanisms of R7-PTX Translocation: Experiments and Molecular Simulations
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 161, 页码: 9
作者:
Wei, Yuping
;
Zhang, Caiying
;
Zhang, Man
;
Niu, Qionghong
;
Hui, Fengli
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/31
Cell penetrating peptide
Molecular dynamic simulation
Synergistic effect
Direct translocation
Endocytosis
Intracellular Paclitaxel Delivery Facilitated by a Dual-Functional CPP with a Hydrophobic Hairpin Tail
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2021, 卷号: 13, 期号: 4, 页码: 4853-4860
作者:
Wei, Yuping
;
Zhang, Man
;
Jiao, Pengfei
;
Zhang, Xin
;
Yang, Ganggang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/03/29
dual-functional peptide
cell penetrating peptide
paclitaxel
intracellular drug delivery
double-proline hairpin tail
帕金森病靶向输递体系用于基因-化药协同治疗的研究
学位论文
: 中国科学院大学, 2020
作者:
刘霖颖
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/07
帕金森病,Sirna,联合递送,仿生设计
Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo.
期刊论文
Drug design, development and therapy, 2019, 卷号: Vol.13, 页码: 1059-1068
作者:
Zhang, CL
;
Ren, WG
;
Liu, QX
;
Tan, ZK
;
Li, JW
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
CPP
IV
NP
cell-penetrating peptide
influenza virus
inhibition
nucleoprotein
siRNA
transportan
Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate
期刊论文
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2018, 卷号: 63
作者:
Ye, Junxiao
;
Pei, Xing
;
Cui, Hui
;
Yu, Zhili
;
Lee, Hyukjin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Cell penetrating peptide
siRNA delivery
Covalent CPP-siRNA chemical conjugate
Cell uptake mechanism
Cytotoxicity
Highly efficient cellular uptake of a cell-penetrating peptide (CPP) derived from the capsid protein of porcine circovirus type 2
期刊论文
The Journal of biological chemistry, 2018, 卷号: 293, 期号: 39, 页码: 15221-15232
作者:
Yu, Wanting
;
Zhan, Yang
;
Xue, Boxin
;
Dong, Yanpeng
;
Wang, Yanfeng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/23
*Circoviridae
*capsid protein
*cell-penetrating peptide (CPP)
*cellular uptake
*endocytosis
*intracellular trafficking
*membrane
*membrane permeability
*nuclear localization signal (NLS)
*permeability
*porcine circovirus virus (PCV)
*protein delivery
*transport vector
Highly efficient cellular uptake of a cell-penetrating peptide derived from the capsid protein of porcine circovirus type 2
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: Vol.293 No.39, 页码: 15221-15232
作者:
Yu, Wanting
;
Zhan, Yang
;
Xue, Boxin
;
Dong, Yanpeng
;
Wang, Yanfeng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/26
cell-penetrating
peptide
(CPP)
membrane
permeability
endocytosis
intracellular
trafficking
cellular
uptake
membrane
permeability
nuclear
localization
signal
(NLS)
porcine
circovirus
virus
(PCV)
protein
delivery
transport
vector
capsid
protein
Circoviridae
Improved method for synthesis of low molecular weight protamine-siRNA conjugate
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 1, 页码: 116-126
作者:
Yu, Zhili
;
Ye, Junxiao
;
Pei, Xing
;
Sun, Lu
;
Liu, Ergang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Cell penetrating peptide
siRNA
Conjugate
Conjugation yield
Biomimetic delivery
Crosslinker
Improved Protein Toxin Delivery Based on ATTEMPTS Systems
期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 4, 页码: 380-392
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Min, Kyoung Ah
;
Wang, Huiyuan
;
Shin, Meong Cheol
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Protein toxin
ribosome-inactivating protein
immunotoxin
cell-penetrating peptide (CPP)
gelonin
tumor-targeting delivery
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