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上海药物研究所 [17]
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期刊论文 [53]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:
Wang, Jun
;
Wang, Lijun
;
Zhang, Shuhong
;
Fan, Junting
;
Yang, Hui
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/10/26
eIF4E/eIF4G
Human lung cancer
Apoptosis
DNA damage
ROS
Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways
期刊论文
LIFE SCIENCES, 2020, 卷号: 243, 页码: 11
作者:
He, Wan
;
Xu, Zhijian
;
Song, Dongliang
;
Zhang, Hui
;
Li, Bo
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  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
Rafoxanide
PTEN/PI3K/AKT
Apoptosis
DNA damage
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Induction of Apoptosis in Human Glioma Cells by Fucoxanthin via Triggering of ROS-Mediated Oxidative Damage and Regulation of MAPKs and PI3K-AKT Pathways
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 8, 页码: 2212, 2219
作者:
Fu, Xiao-yan
;
Fan, Cun-dong
;
Wang, Ying
;
Ma, Jin-kui
;
Hou, Ya-jun
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  |  
浏览/下载:186/0
  |  
提交时间:2019/09/09
fucoxanthin
glioma cells
reactive oxygen species
apoptosis
oxidative damage
Genistein attenuates pathological cardiac hypertrophy in vivo and in vitro
期刊论文
HERZ, 2019, 卷号: 44, 期号: 3
作者:
Meng, Y.
;
Zhang, Y.
;
Ma, Z.
;
Zhou, H.
;
Ni, J.
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Protein kinase inhibitors
Cardiomegaly
Endomyocardial fibrosis
Mitogen-activated protein kinase phosphatase
JNK1/2 kinase
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages
期刊论文
International Journal of Molecular Sciences, 2018
作者:
Jingyu He
;
Xianyuan Lu
;
Yaqian Dong
;
Zheng Cai
;
Lan Tang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/31
A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma
期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 12, 页码: 3256-3267
作者:
Sun, Jingya
;
Wang, Xin
;
Tang, Boyun
;
Liu, Hongchun
;
Zhang, Minmin
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  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
dasatinib
YAP
Src
renal cell carcinoma
JNK pathway in osteosarcoma: pathogenesis and therapeutics.
期刊论文
Journal of receptor and signal transduction research, 2016, 卷号: 36, 期号: 5, 页码: 465-470
作者:
Li, Yu-Sheng
;
Deng, Zhen-Han
;
Zeng, Chao
;
Lei, Guang-Hua*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
*JNK inhibitors
*c-Jun NH2-terminal kinase pathway
*matrix metalloproteinase
*mitogen-activated protein kinase
*osteosarcoma
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