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科研机构
上海药物研究所 [33]
内容类型
期刊论文 [33]
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2021 [2]
2020 [1]
2019 [3]
2018 [4]
2017 [1]
2016 [3]
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Pharmacolo... [2]
Chemistry [1]
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Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6
作者:
Hu, Yu
;
Zou, Xiangman
;
Shi, Weiwei
;
Ma, Chenhui
;
Chen, Feifei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Vancomycin C-terminus modification
Hydrazide derivatives
Native Chemical Ligation
Antibacterial activity
Structurally diverse halosesquiterpenoids from the red alga Laurencia composita Yamada
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Hu, Zhi-Biao
;
Yu, Xiao-Qing
;
Wang, Bin
;
Liu, Ai-Hong
;
Zhao, Tian-Sheng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Laurencia composita
Chamigrane sesquiterpenoids
Bisabolane sesquiterpenoids
Nerolidol derivative
Modified Mosher's method
Antifungal activity
Antibacterial activity
Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents
期刊论文
ARCHIV DER PHARMAZIE, 2019, 页码: 13
作者:
Ding, Shi
;
Ji, Jing-Chao
;
Zhang, Ming-Juan
;
Yang, Yu-She
;
Wang, Rui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
oxazolidine
QSAR
Synthesis and In Vitro Antibacterial Activity of Novel Naphthyridinone Derivatives
期刊论文
CHEMISTRYSELECT, 2019, 卷号: 4, 期号: 21, 页码: 6552-6556
作者:
Sun, Bin
;
Chen, Jianwei
;
Ye, Fei
;
Lu, Yaojia
;
Xu, Guiqing
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
antibacterial activity
C
violaceum ATCC 12472
naphthyridinone derivatives
quorum sensing inhibitory activity
synthesis
Integration of multiscale molecular modeling approaches with the design and discovery of fusidic acid derivatives
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 12, 页码: 1427-1442
作者:
Lu, Jing
;
Ni, Ling-Xuan
;
Wang, Jin-An
;
Liu, Ze-Yun
;
Shang, Kang-Le
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
docking
fusidic acid
half-life
molecular dynamic simulation
pharmacokinetics
Design and synthesis of C-10 modified and ring-truncated canthin-6-one analogues as effective membrane-active antibacterial agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 18, 页码: 3123-3128
作者:
Dai, Jiangkun
;
Dan, Wenjia
;
Zhang, Yunyun
;
He, Mengfan
;
Wang, Junru
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Canthin-6-one
Synthesis
Antibacterial activity
Structure-activity relationships
Mechanism
Design and Synthesis of Pyrophosphate-Targeting Vancomycin Derivatives for Combating Vancomycin-Resistant Enterococci
期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 16, 页码: 1644-1657
作者:
Guan, Dongliang
;
Chen, Feifei
;
Faridoon
;
Liu, Junjie
;
Li, Jian
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
antibacterial activity
click chemistry
Mannich reaction
pyrophosphate
vancomycin
Synthesis and antibacterial activity of C-2 or C-5 modified and D ring rejiggered canthin-6-one analogues
期刊论文
FOOD CHEMISTRY, 2018, 卷号: 253, 页码: 211-220
作者:
Dai, Jiangkun
;
Dan, Wenjia
;
Li, Nian
;
Wang, Ruixue
;
Zhang, Yao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Synthesis
Canthin-6-one analogues
Antibacterial
Structure-activity relationships
Cell membrane
DNA topoisomerases
Design, synthesis and biological evaluation of C(4) substituted monobactams as antibacterial agents against multidrug-resistant Gram-negative bacteria
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 98-109
作者:
Kou, Qunhuan
;
Wang, Ting
;
Zou, Feng
;
Zhang, Shuhua
;
Chen, Qian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Monobactam
C(4) substituents
Pyridone
MDR Gram-negative bacteria
Antibacterial activity
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