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科研机构
北京大学 [19]
内容类型
期刊论文 [19]
发表日期
2017 [1]
2016 [2]
2015 [1]
2014 [1]
2013 [1]
2012 [4]
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专题:北京大学
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In vitro and in vivo evaluation of a Cu-64-labeled propylene amine oxime complex as a potential hypoxia imaging agent bearing two 3-nitrotriazole groups
期刊论文
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2017
Zhang, Wei
;
Zhang, Qiang
;
Chen, Qingxin
;
Zhu, Hua
;
Yang, Zhi
;
Chu, Taiwei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
Tumor hypoxia
3-Nitrotriazole
PET imaging
PnAO
TARGETING TUMOR HYPOXIA
BIOLOGICAL EVALUATION
COPPER-64 RADIOPHARMACEUTICALS
RESISTANCE MECHANISMS
NITROIMIDAZOLE DRUGS
PET
LIGANDS
MARKERS
CANCER
THERAPY
Phosphorylation of PPAR gamma at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4
期刊论文
Oncotarget, 2016
Shu, Yuxin
;
Lu, Yan
;
Pang, Xiaojuan
;
Zheng, Wei
;
Huang, Yahong
;
Li, Jiahong
;
Ji, Jianguo
;
Zhang, Can
;
Shen, Pingping
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
phosphorylation
PPAR gamma
PFKFB4
hepatocellular carcinoma
glycolysis
ACTIVATED PROTEIN-KINASE
LIVER-CANCER
RECEPTOR-GAMMA
TUMOR-GROWTH
MOUSE MODEL
METABOLISM
INHIBITOR
HYPOXIA
DYSREGULATION
ADIPOGENESIS
In vitro and in vivo evaluation of technetium-99m-labeled propylene amine oxime complexes containing nitroimidazole and nitrotriazole groups as hypoxia markers
期刊论文
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2016
Zhang, Qiang
;
Huang, Huafan
;
Chu, Taiwei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
technetium-99m
PnAO
nitroimidazole
nitrotriazole
hypoxia
TUMOR HYPOXIA
BIOLOGICAL EVALUATION
IMAGING HYPOXIA
IODOAZOMYCIN ARABINOSIDE
AGENT
BISNITROIMIDAZOLE
METRONIDAZOLE
CANCER
2-NITROIMIDAZOLE
OPPORTUNITIES
In vivo click reaction between Tc-99m-labeled azadibenzocyclooctyne-MAMA and 2-nitroimidazole-azide for tumor hypoxia targeting
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015
Sun, Wenjing
;
Chu, Taiwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
Tumor hypoxia
2-Nitroimidazole
Tc-99m-labeling
Pretargeting
SPAAC
AZIDE-ALKYNE CYCLOADDITION
COPPER-FREE CLICK
DEVELOPING ZEBRAFISH
LIVING SYSTEMS
LIVE MICE
CHEMISTRY
THERAPY
TC-99M
CANCER
RADIOIMMUNOTHERAPY
Synthesis and biological evaluation of novel (TcN)-Tc-99m-labeled bisnitroimidazole complexes containing monoamine-monoamide dithiol as potential tumor hypoxia markers
期刊论文
journal of radioanalytical and nuclear chemistry, 2014
Mei, Lei
;
Sun, Wenjing
;
Chu, Taiwei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/11/10
Tumor hypoxia
Radiolabeling
MAMA
Bisnitroimidazole
Technetium-nitrido complex
IN-VITRO
IMAGING HYPOXIA
AGENTS
RADIOPHARMACEUTICALS
DERIVATIVES
ANALOGS
TC-99M
CANCER
Preparation and biological evaluation of Tc-99m-N4IPA for single photon emission computerized tomography imaging of hypoxia in mouse tumor
期刊论文
欧洲医药化学杂志, 2013
Li, Nan
;
Zhu, Hua
;
Chu, Tai-wei
;
Yang, Zhi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/11
Technium-99m
4-Nitroimidazoles
Hypoxia imaging
Tumor
IN-VITRO
TC-99M-LABELED 2-NITROIMIDAZOLE
CHELATING MOIETY
CELLS-INVITRO
COMPLEXES
MARKER
RADIOPHARMACEUTICALS
4-NITROIMIDAZOLE
HYDROXAMAMIDE
PIMONIDAZOLE
Recent Advances on Radionuclide Labeled Hypoxia-Imaging Agents
期刊论文
current pharmaceutical design, 2012
Li, Zejun
;
Chu, Taiwei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/13
Radionuclide
tumor
hypoxia imaging agent
nitroimidazole
redox-sensitive compounds
POSITRON-EMISSION-TOMOGRAPHY
CARBONIC-ANHYDRASE INHIBITORS
SQUAMOUS-CELL CARCINOMA
IN-VIVO EVALUATION
TUMOR HYPOXIA
BIOLOGICAL EVALUATION
TISSUE HYPOXIA
NECK-CANCER
BIS(THIOSEMICARBAZONATO) COMPLEXES
COPPER RADIOPHARMACEUTICALS
Synthesis, Radiolabeling and Biological Evaluation of Propylene Amine Oxime Complexes Containing Nitrotriazoles as Hypoxia Markers
期刊论文
molecules, 2012
Huang, Huafan
;
Mei, Lei
;
Chu, Taiwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/13
nitrotriazole
technetium-99m
tumor
hypoxia marker
cellular accumulation
POSITRON-EMISSION-TOMOGRAPHY
BRAIN-IMAGING AGENTS
TUMOR HYPOXIA
IN-VITRO
TC-99M-LABELED 2-NITROIMIDAZOLE
LIGANDS
AK-2123
RADIOPHARMACEUTICALS
METRONIDAZOLE
ACCUMULATION
99(m)Tc/Re complexes bearing bisnitroimidazole or mononitroimidazole as potential bioreductive markers for tumor: Synthesis, physicochemical characterization and biological evaluation
期刊论文
欧洲医药化学杂志, 2012
Mei, Lei
;
Wang, Yue
;
Chu, Taiwei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/11/10
Bisnitroimidazole
Technetium
Rhenium
Tumor hypoxia
Biodistribution
IN-VIVO EVALUATION
HYPOXIC CELLS
VITRO
TC-99M
CANCER
AGENT
DRUGS
F-18-FLUOROMISONIDAZOLE
4-NITROIMIDAZOLE
BIODISTRIBUTION
Effect of a second nitroimidazole redox centre on the accumulation of a hypoxia marker: Synthesis and in vitro evaluation of Tc-99m-labeled bisnitroimidazole propylene amine oxime complexes
期刊论文
生物有机化学与医药化学通讯, 2012
Huang, Huafan
;
Zhou, Hao
;
Li, Zejun
;
Wang, Xiangyun
;
Chu, Taiwei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/11/10
Bisnitroimidazole
Technetium-99m
Hypoxia
Cellular accumulation
PnAO
BRAIN-IMAGING AGENTS
IODOAZOMYCIN ARABINOSIDE
CANCER-THERAPY
TUMOR HYPOXIA
LIGANDS
TISSUE
2-NITROIMIDAZOLE
METRONIDAZOLE
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