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科研机构
上海药物研究所 [58]
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期刊论文 [58]
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2021 [2]
2020 [2]
2019 [5]
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内容类型:期刊论文
专题:上海药物研究所
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Effects of Shuanghuanglian oral liquids on patients with COVID-19: a randomized, open-label, parallel-controlled, multicenter clinical trial
期刊论文
FRONTIERS OF MEDICINE, 2021, 页码: 14
作者:
Ni, Li
;
Wen, Zheng
;
Hu, Xiaowen
;
Tang, Wei
;
Wang, Haisheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
COVID-19
SARS-CoV-2
Shuanghuanglian oral liquid
clinical trial
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
;
Long, Xiubing
;
Jiang, Kailong
;
Song, Pinrao
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Liver-Target and Glucose-Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 15
作者:
Wang, Aohua
;
Fan, Weiwei
;
Yang, Tiantian
;
He, Shufang
;
Yang, Yiwei
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
glucose responsive
insulin secretion
liver target
oral drug delivery
polymersomes
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
NPC1L1-Targeted Cholesterol-Grafted Poly(beta-Amino Ester)/pDNA Complexes for Oral Gene Delivery
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2019, 卷号: 8, 期号: 8, 页码: 12
作者:
Liu, Yuan
;
Chen, Dan
;
Li, Jialin
;
Xia, Dengning
;
Yu, Miaorong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
cellular uptake
cholesterol
oral gene delivery
transfection efficiency
Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus-PVPVA complex
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 1, 页码: 107-117
作者:
Zhu, Chunliu
;
Gong, Shuang
;
Ding, Jinsong
;
Yu, Miaorong
;
Ahmad, Ejaj
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2020/07/01
Silybin
Soluplus
PVPVA
Complex
Supersaturated drug delivery system
Oral bioavailability
recentprogressindrugdelivery
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1145
作者:
Li Chong
;
Wang Jiancheng
;
Wang Yiguang
;
Gao Huile
;
Wei Gang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
MESOPOROUS SILICA NANOPARTICLES
IN-VIVO PHARMACOKINETICS
ORAL DELIVERY
SIRNA DELIVERY
TARGETED NANOASSEMBLIES
CANCER-IMMUNOTHERAPY
COMBINATION THERAPY
SENSITIVE VESICLES
MEMBRANE-RECEPTORS
TUMOR PENETRATION
Pharmaceutics
Drug delivery system
Basic research
Application
Delivery strategy
supersaturatedpolymericmicellesfororalsilybindeliverytheroleofthesolupluspvpvacomplex
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 1, 页码: 107
作者:
Zhu Chunliu
;
Gong Shuang
;
Ding Jinsong
;
Yu Miaorong
;
Ahmad Ejaj
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
SOLUBILITY-PERMEABILITY INTERPLAY
WATER-SOLUBLE DRUGS
MEMBRANE-TRANSPORT
FORMULATION DESIGN
IN-VITRO
SYSTEM
BIOAVAILABILITY
ABSORPTION
IMPACT
DISSOLUTION
Silybin
Soluplus
PVPVA
Complex
Supersaturated drug delivery system
Oral bioavailability
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
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