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科研机构
湖南大学 [4]
中国医学科学院 北京... [2]
南华大学 [1]
上海药物研究所 [1]
昆明医科大学 [1]
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期刊论文 [9]
发表日期
2019 [9]
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发表日期:2019
内容类型:期刊论文
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Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:
Zhu, Kongkai
;
Shao, Jingwei
;
Tao, Hongrui
;
Yan, Xue
;
Luo, Cheng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
PRMT5 inhibitor
Anti-proliferative
Cellular target validation
Design and synthesis
Novel Resveratrol-chalcone Derivatives: Synthesis and Biological Evaluation
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 5
作者:
Liu, Bei
;
Zhu, Ping
;
Zheng, Xi
;
Ma, Yulu
;
Wan, Chunping
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/04
Resveratrol
chalcon
anti-inflammatory activity
anti-proliferative activity
FACs analysis
inflammation
Anti-proliferative activity and structure-activity relationship of honokiol derivatives
期刊论文
Bioorganic & Medicinal Chemistry, 2019
作者:
Ding Lin
;
Zhongzhong Yan
;
Aiyu Chen
;
Jiao Ye
;
Aixi Hu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/13
Honokiol
Anti-proliferative
Structure-activity relationship
3D-QASR
Theoretical calculations
Anti-proliferative activity and structure-activity relationship of honokiol derivatives.
期刊论文
Bioorganic & medicinal chemistry, 2019
作者:
Lin, D
;
Yan, ZZ
;
Chen, AY
;
Ye, J
;
Hu, AX
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/13
3D-QASR
Anti-proliferative
Honokiol
Structure-activity relationship
Theoretical calculations
Supercritical CO fluid extraction of Croton crassifolius Geisel root: chemical composition and anti-proliferative, autophagic, apoptosis-inducing, and related molecular effects on A549 tumour cells
期刊论文
Phytomedicine, 2019, 页码: 152846
作者:
Chao Liu
;
Rui-rui Zhang
;
Yue-ming Wang
;
Jing Zhang
;
Qing Wang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
Croton
crassifolius
essential
oil
Anti-proliferative
Apoptosis-inducing
Molecular
mechanism
Design, synthesis and in vitro biological evaluation of novel 4-methoxy-5-hydroxycanthin-6-one derivatives as potential anti-tumor agents.
期刊论文
Natural product research, 2019, 页码: 1-6
作者:
Dai Weiqiang
;
He Jinfeng
;
Ye Feng
;
Xu Jian
;
Liu Wenyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
4-methoxy-5-hydroxycanthin-6-one
Picrasma
quassioides
anti-proliferative
activity
apoptosis
western
blot
Inhibition of cancer cell growth by Tangeretin flavone in drug-resistant MDA-MB-231 human breast carcinoma cells is facilitated via targeting cell apoptosis, cell cycle phase distribution, cell invasion and activation of numerous Caspases
期刊论文
2019, 卷号: 24, 期号: 4, 页码: 1532-1537
作者:
Fan, Shanji
;
Xu, Haifan
;
Liu, Hongguang
;
Hu, Zecheng
;
Xiao, Junyan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
Tangeretin
breast cancer
anti-proliferative effect
cell cycle
caspases
Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration
期刊论文
2019, 卷号: 24, 期号: 5
作者:
Yang, Kun
;
Jin, Ming-Ji
;
Quan, Zhe-Shan
;
Piao, Hu-Ri
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
emodin derivatives
amino acids
anti-proliferative activity
HepG2 cells
MCF-7 cells
Anti-proliferative activity and structure-activity relationship of honokiol derivatives
期刊论文
Bioorganic and Medicinal Chemistry, 2019, 卷号: 27, 期号: 16, 页码: 3729-3734
作者:
Lin, Ding
;
Yan, Zhongzhong
;
Chen, Aiyu
;
Ye, Jiao
;
Hu, Aixi*
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
3D-QASR
Anti-proliferative
Honokiol
Structure-activity relationship
Theoretical calculations
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