CORC

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CORC

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Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu
收藏  |  浏览/下载：41/0  |  提交时间：2021/12/01
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie
收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen
收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01
A patent review of BRD4 inhibitors (2013-2019) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81
作者:  Lu, Tian;  Lu, Wenchao;  Luo, Cheng
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan
收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:  Chen, Deheng;  Lu, Tian;  Yan, Ziqin;  Lu, Wenchao;  Lyu, Xilin
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Design, Synthesis, and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 2950-2973
作者:  Shi, Chenghui;  Zhang, Yinyong;  Wang, Ting;  Lu, Wenchao;  Zhang, Shuhua
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01

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