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科研机构
上海药物研究所 [28]
内容类型
期刊论文 [20]
会议论文 [8]
发表日期
2021 [2]
2020 [2]
2018 [3]
2015 [1]
2014 [1]
2013 [1]
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Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhang, Wan-ting
;
Liu, Ting-ting
;
Wu, Man
;
Chen, Xiao-chen
;
Han, Li
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
nanobody
FGL1
cancer immunology
diagnosis
immune checkpoint
Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Wu, Shou-yan
;
Wang, Wen-jie
;
Dou, Jin-hui
;
Gong, Li-kun
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
18 beta-glycyrrhetic acid
licorice preparation
liver injury
glycyrrhetinic acid target
A new recombinant MS-superoxide dismutase alleviates 5-fluorouracil-induced intestinal mucositis in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 348-357
作者:
Yan, Xiao-xia
;
Li, Hai-long
;
Zhang, Yi-ting
;
Wu, Shou-yan
;
Lu, Heng-lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
;
Wang, Le
;
Zhang, Yi-Ting
;
Yan, Xiao-Xia
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Zhang, Yi-Ting
;
Yu, Yu-Qi
;
Yan, Xiao-Xia
;
Wang, Wen-Jie
;
Tian, Xiao-Ting
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
Lysophospholipids from the Guangxi Sponge Spirastrella purpurea
期刊论文
LIPIDS, 2015, 卷号: 50, 期号: 7, 页码: 697-703
作者:
Lin, Kun
;
Yang, Peng
;
Yang, Hui
;
Liu, Ai-Hong
;
Yao, Li-Gong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Sponge
Spirastrella purpurea
Marine natural products
Lysophospholipids
Guangxi
Antifungal activity
Neuroprotective activity
HPLC
NMR
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 292-300
作者:
Yao, Jun
;
Li, Cheng-gang
;
Gong, Li-kun
;
Feng, Chen-chen
;
Li, Chun-zhu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9, 页码: 1229-1236
作者:
Qi, Xin-ming
;
Miao, Ling-ling
;
Cai, Yan
;
Gong, Li-kun
;
Ren, Jin
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
tetrandrine
mitochondria
reactive oxygen species
cytochrome P450
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