×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [12]
内容类型
期刊论文 [11]
会议论文 [1]
发表日期
2018 [5]
2017 [1]
2016 [2]
2015 [1]
2014 [2]
2012 [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共12条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation
期刊论文
NANO LETTERS, 2018, 卷号: 18, 期号: 4, 页码: 2411-2419
作者:
He, Shufang
;
Fan, Weiwei
;
Wu, Na
;
Zhu, Jingjing
;
Miao, Yunqiu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Lipids
liquid crystalline nanoparticles
siRNA delivery
endosomal escape
synthetic lethality
Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections
期刊论文
ACS INFECTIOUS DISEASES, 2018, 卷号: 4, 期号: 3, 页码: 208-217
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Chen, Feifei
;
Mao, Fei
;
Wei, Hanwen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Staphylococcus aureus
diapophytoene desaturase
methicillin-resistant Staphylococcus aureus
hERG safety
Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 233-237
作者:
Ni, Shuaishuai
;
Li, Baoli
;
Chen, Feifei
;
Wei, Hanwen
;
Mao, Fei
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Virulence factor
pigment
multidrug resistant MRSA
CrtN inhibitor
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 235-251
作者:
Wei, Hanwen
;
Mao, Fei
;
Ni, Shuaishuai
;
Chen, Feifei
;
Li, Baoli
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
CrtN inhibitor
STX biosynthesis
Pigment inhibitory activity
Resistant S. aureus
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 224-250
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Mao, Fei
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19, 页码: 8145-8159
作者:
Ni, Shuaishuai
;
Wei, Hanwen
;
Li, Baoli
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN)
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 10, 页码: 4831-4848
作者:
Wang, Youxin
;
Di, Hongxia
;
Chen, Feifei
;
Xu, Yong
;
Xiao, Qiang
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 7, 页码: 3215-3230
作者:
Wang, Youxin
;
Chen, Feifei
;
Di, Hongxia
;
Xu, Yong
;
Xiao, Qiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
methylationanditsroleinthedispositionoftanshinolacardiovascularcarboxyliccatecholfromsalviamiltiorrhizarootsdanshen
期刊论文
actapharmacologicasinica, 2015, 卷号: 36, 期号: 5, 页码: 627
作者:
Tian Dandan
;
Jia Weiwei
;
Liu Xinwei
;
Wang Dandan
;
Liu Junhua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
HERB-DRUG INTERACTIONS
O-METHYLTRANSFERASE
PLASMA HOMOCYSTEINE
PARKINSONS-DISEASE
CYTOSOLIC SULFOTRANSFERASE
ENDOTHELIAL DYSFUNCTION
MOLECULAR-MECHANISMS
DANHONG INJECTION
SYSTEMIC EXPOSURE
AQUEOUS EXTRACT
tanshinol
methylation
catechol-O-methyltransferase
herb-drug interaction
Salvia miltiorrhiza roots
Danshen
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 卷号: 111, 期号: 37, 页码: 13517-13522
作者:
Zhang, Jie
;
Liu, Hongchuan
;
Zhu, Kongkai
;
Gong, Shouzhe
;
Dramsi, Shaynoor
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
nosocomial infection
LPXTG motif
antivirulence
computational screening
©版权所有 ©2017 CSpace - Powered by
CSpace