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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
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2022 [1]
2021 [3]
2020 [2]
2019 [3]
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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:
Qiu, Yunguang
;
Huang, Lu
;
Fu, Jie
;
Han, Chenxia
;
Fang, Jing
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Engineering nanoparticles to locally activate T cells in the tumor microenvironment
期刊论文
SCIENCE IMMUNOLOGY, 2019, 卷号: 4, 期号: 37, 页码: 13
作者:
Wang, Dangge
;
Wang, Tingting
;
Yu, Haijun
;
Feng, Bing
;
Zhou, Lei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade
期刊论文
ADVANCED MATERIALS, 2019, 卷号: 31, 期号: 14, 页码: 11
作者:
Zhou, Fangyuan
;
Feng, Bing
;
Yu, Haijun
;
Wang, Dangge
;
Wang, Tingting
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
cancer immunotherapy
CD47 blockade
immunogenic cell death
prodrug vesicles
tumor microenvironment
Sensitive Water-Soluble Fluorescent Probe Based on Umpolung and Aggregation-Induced Emission Strategies for Selective Detection of Hg2+ in Living Cells and Zebrafish
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 8, 页码: 2377-2383
作者:
Gao, Tang
;
Huang, Xueyan
;
Huang, Shuai
;
Dong, Jie
;
Yuan, Kai
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
umpolung
aggregation-induced emission
fluorescent probe
detection of Hg2+
cell imaging
zebrafish imaging
Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment
期刊论文
ADVANCED MATERIALS, 2018, 卷号: 30, 期号: 38
作者:
Feng, Bing
;
Zhou, Fangyuan
;
Hou, Bo
;
Wang, Dangge
;
Wang, Tingting
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
immune tumor microenvironment
immunogenic cell death
immunotherapy
prodrug nanoparticles
stimuli-activation
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