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科研机构
大连理工大学 [17]
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期刊论文 [15]
会议论文 [2]
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2019 [1]
2017 [1]
2016 [2]
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专题:大连理工大学
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Systems pharmacology uncover the mechanism of anti-non-small cell lung cancer for Hedyotis diffusa Willd
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 109, 页码: 969-984
作者:
Su, Xing
;
Li, Yueping
;
Jiang, Meng
;
Zhu, Jinglin
;
Zheng, Chunli
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/02
Hedyotis diffusa Willd
Antitumor
Systems pharmacology
Non-small cell lung cancer
Traditional Chinese medicine
Large-scale cross-species chemogenomic platform proposes a new drug discovery strategy of veterinary drug from herbal medicines
期刊论文
PLOS ONE, 2017, 卷号: 12, 页码: e0184880
作者:
Huang, Chao
;
Yang, Yang
;
Chen, Xuetong
;
Wang, Chao
;
Li, Yan
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
New strategy for drug discovery by large-scale association analysis of molecular networks of different species
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 21872
作者:
Zhang, Bo
;
Fu, Yingxue
;
Huang, Chao
;
Zheng, Chunli
;
Wu, Ziyin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/09
A novel systems pharmacology platform to dissect action mechanisms of traditional Chinese medicines for bovine viral diarrhea disease
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 卷号: 94, 页码: 33-45
作者:
Zheng, Chunli
;
Pei, Tianli
;
Huang, Chao
;
Chen, Xuetong
;
Bai, Yaofei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/09
Systems pharmacology
Bovine viral diarrhea (BVD)
Traditional Chinese medicines
Therapeutic mechanisms
Huangqin Zhizi formula
Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM
期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2015, 卷号: 2015, 页码: 980190
作者:
Wang, Yonghua
;
Zheng, Chunli
;
Huang, Chao
;
Li, Yan
;
Chen, Xuetong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/09
Large-scale exploration and analysis of drug combinations
期刊论文
BIOINFORMATICS, 2015, 卷号: 31, 页码: 2007-2016
作者:
Li, Peng
;
Huang, Chao
;
Fu, Yingxue
;
Wang, Jinan
;
Wu, Ziyin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/09
Large-scale Direct Targeting for Drug Repositioning and Discovery
期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5, 页码: 11970
作者:
Zheng, Chunli
;
Guo, Zihu
;
Huang, Chao
;
Wu, Ziyin
;
Li, Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/09
Systems pharmacology in drug discovery and therapeutic insight for herbal medicines
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2014, 卷号: 15, 页码: 710-733
作者:
Huang, Chao
;
Zheng, Chunli
;
Li, Yan
;
Wang, Yonghua
;
Lu, Aiping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
systems pharmacology
herbal medicines
ADME
network pharmacology
depression
A Systems-Pharmacology Analysis of Herbal Medicines Used in Health Improvement Treatment: Predicting Potential New Drugs and Targets
期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 卷号: 2013, 页码: 938764
作者:
Liu, Jianling
;
Pei, Mengjie
;
Zheng, Chunli
;
Li, Yan
;
Wang, Yonghua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Comparative molecular dynamics simulations of histone deacetylase-like protein: Binding modes and free energy analysis to hydroxamic acid inhibitors
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2008, 卷号: 73, 页码: 134-149
作者:
Yan, Chunli
;
Xiu, Zhilong
;
Li, Xiaohui
;
Li, Shenmin
;
Hao, Ce
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
histone deacetylase
histone deacetylase-like protein
molecular dynamics simulation
molecular mechanics-Poisson-Boltzmann surface area (MM-PBSA) method
molecular mechanics generalized Born surface area (MM-GBSA)
mutagenesis
hydroxamic acid inhibitor
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