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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704
作者:  Qin, Chong;  Hu, Yang;  Zhou, Bing;  Fernandez-Salas, Ester;  Yang, Chao-Yie
收藏  |  浏览/下载:45/0  |  提交时间:2019/01/08
Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 14, 页码: 6110-6120
作者:  Zhao, Yujun;  Zhou, Bing;  Bai, Longchuan;  Liu, Liu;  Yang, Chao-Yie
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 9, 页码: 3887-3901
作者:  Zhao, Yujun;  Bai, Longchuan;  Liu, Liu;  McEachern, Donna;  Stuckey, Jeanne A.
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Design, Synthesis and Evaluation of Tricyclic, Conformationally Constrained Smac Mimetics As Antagonists of IAP Proteins 期刊论文
J. Med. Chem., 2008, 卷号: 51, 期号: 23, 页码: 7352-7355
ZHANG BIN; ZANETA NIKOLOVSKA-COLESKA; ZHANG YAN; BAI LONGCHUAN; QIU SU; YANG CHAOYIE; SUN HAIYING; 王少萌; 伍贻康
收藏  |  浏览/下载:12/0  |  提交时间:2013/02/25


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