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浏览/检索结果: 共43条，第1-10条 帮助 限定条件 内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16 Temperature-Controlled Divergent Synthesis of Tetrasubstituted Alkenes and Pyrrolo[1,2-a]indole Derivatives via Iridium Catalysis 期刊论文 ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 页码: 14 作者:  Liu, Siyu;  Mao, Hui;  Qiao, Jin;  Zhang, Xiaoning;  Lu, Yangbin 收藏  |  浏览/下载：73/0  |  提交时间：2021/11/04 Iridium  C-H activation  [3+2] annulation  Tetrasubstituted alkene  pyrrolo[1,2-a]indole   Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function 期刊论文 CELL RESEARCH, 2021, 页码: 18 作者:  Xu, Xiang;  Ding, Guangjin;  Liu, Caizhi;  Ding, Yuhan;  Chen, Xiaoxin 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms 期刊论文 CELL REPORTS, 2021, 卷号: 36, 期号: 7, 页码: 20 作者:  Zhou, Zikai;  He, Guiqin;  Zhang, Xiaoyun;  Lv, Xin;  Zhang, Xiaolin 收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04 Rh(III)-Catalyzed Divergent Synthesis of Alkynylated Imidazo[1,5-a]indoles and alpha,alpha-Difluoromethylene Tetrasubstituted Alkenes 期刊论文 ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5766-5771 作者:  Zhao, Fei;  Qiao, Jin;  Lu, Yangbin;  Zhang, Xiaoning;  Dai, Long 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 Redox-Neutral Rhodium(III)-Catalyzed Chemospecific and Regiospecific [4+1] Annulation between Indoles and Alkenes for the Synthesis of Functionalized Imidazo[1,5-a]indoles 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 15, 页码: 10591-10607 作者:  Zhao, Fei;  Qiao, Jin;  Lu, Yangbin;  Zhang, Xiaoning;  Dai, Long 收藏  |  浏览/下载：32/0  |  提交时间：2021/11/04 Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing 期刊论文 CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924 作者:  Mao, Rui;  Zhang, Xiaoyun;  Kong, Youyong;  Wu, Shanshan;  Huo, Hai-qin 收藏  |  浏览/下载：34/0  |  提交时间：2021/08/17 anaplastic lymphoma kinase  cerebral organoid  neurodevelopment  neural progenitor cell  single-cell RNA sequencing