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科研机构
上海药物研究所 [10]
内容类型
期刊论文 [10]
发表日期
2021 [10]
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发表日期:2021
专题:上海药物研究所
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Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Styryl pyranones with apoptosis activities from the sporocarps of Phellinus igniarius
期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 44, 页码: 154-159
作者:
Cao, Yinglong
;
Liu, Yi
;
Wang, Ge
;
Wang, Wenqiong
;
Li, Yougui
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Phellinus igniarius
Styryl pyranones
Cell apoptosis
Neolinulicin A and B from Inula japonica and their anti-inflammatory activities
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 6
作者:
Wu, Rui-fang
;
Zhou, Bing-duo
;
Wang, Wen-qiong
;
Chen, Tong
;
Xu, Ting-ting
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Inula japonica
Sesquiterpenes
Anti-inflammation
Anti-inflammatory sesquiterpene dimers and diterpenes from the aerial part of Inula japonica
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 页码: 8
作者:
Wu, Rui-Fang
;
Wang, Wen-Qiong
;
Zhou, Bing-Duo
;
Wang, Yi
;
Li, Ya-Ding
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
Anti-inflammation
composite
ent-kaurane diterpenes
Inula japonica
sesquiterpene dimers
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA
Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure
期刊论文
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2021, 卷号: 10, 期号: 6, 页码: 33
作者:
Li, Xuan
;
Lu, Qingguo
;
Qiu, Yunguang
;
do Carmo, Jussara M.
;
Wang, Zhen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
cardiac hypertrophy
cardiac metabolism
cardiomyocytes
sodium glucose cotransporter 2
transverse aortic constriction
Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xuan
;
Dong, Ying
;
Li, Wan-chen
;
Tang, Bi-xi
;
Li, Jia
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
idiopathic pulmonary fibrosis
cellular senescence
roxithromycin
NOX4
senescence-associated secretory phenotype (SASP)
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
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