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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 9 作者:  Wang, Yue;  Guo, Shimeng;  Zhuang, Youwen;  Yun, Ying;  Xu, Peiyu 收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages 期刊论文 NANO LETTERS, 2021, 卷号: 21, 期号: 14, 页码: 6031-6041 作者:  Chen, Mingshu;  Miao, Yunqiu;  Qian, Kun;  Zhou, Xin;  Guo, Linmiao 收藏  |  浏览/下载：28/0  |  提交时间：2021/11/04 Immunochemotherapy  triple-negative breast cancer  liposomes  tumor-associated macrophages  MMP2 response   Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8644-8665 作者:  Kong, Qidi;  Pan, Wei;  Xu, Heng;  Xue, Yaru;  Guo, Bin 收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17 Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu 收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17 furmonertinib (alflutinib  AST2818)  quantitative proteomics  sandwich-cultured human hepatocytes   Improved Practical Synthesis of DY-038, an Oral Available Antiplatelet Agent 期刊论文 CHEMISTRYSELECT, 2021, 卷号: 6, 期号: 13, 页码: 3183-3186 作者:  Cao, Yangzhi;  Kong, Deyu;  Sun, Lulu;  Meng, Xin;  Zhang, Yinyong 收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 antiplatelet agent  cyclization  DY-038  process development  sulfonamides   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：147/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yong-zhen;  Lu, Heng-lei;  Qi, Xin-ming;  Xing, Guo-zhen;  Wang, Xin 收藏  |  浏览/下载：71/0  |  提交时间：2021/05/24 aristolochic acid I  glutathione S-transferase placental form-positive foci  clonal expansion  hepatocellular carcinoma  medium-term rat liver bioassay  DNA adducts   GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957 作者:  Wang, Congcong;  Zhang, Yu-Fang;  Guo, Shimeng;  Zhao, Quan;  Zeng, Yanping 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24