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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文 PROTEIN & CELL, 2021, 页码: 21 作者:  Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 drug target inference  transcriptomics  deep learning  experimental verification   The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability 期刊论文 MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+ 作者:  Pan, Qiang;  Zhong, Shanshan;  Wang, Hanling;  Wang, Xuege;  Li, Ni 收藏  |  浏览/下载：76/0  |  提交时间：2021/11/04 Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11 作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu 收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17 Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002 作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye 收藏  |  浏览/下载：25/0  |  提交时间：2021/08/17 Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7 作者:  Pan, Lu-lu;  Chen, Tao;  Hui, Min;  Wang, Shuo;  Fu, Li 收藏  |  浏览/下载：131/0  |  提交时间：2021/05/24 LC-MS/MS  Forsythin  Aglycone glucuronide  Aglycone sulfate  Pharmacokinetics   Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory 期刊论文 MOLECULAR PSYCHIATRY, 2021, 页码: 19 作者:  Wang, Yu-Jun;  Yu, Chuan;  Wu, Wei-Wei;  Ju, Yun-Yue;  Liu, Yao 收藏  |  浏览/下载：81/0  |  提交时间：2021/06/11 Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：81/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：81/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity 期刊论文 MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177 作者:  Chen, Zhong-Guo;  Wang, Yu-Jun;  Chen, Ruo-Song;  Geng, Fan;  Gan, Chen-Ling 收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yong-zhen;  Lu, Heng-lei;  Qi, Xin-ming;  Xing, Guo-zhen;  Wang, Xin 收藏  |  浏览/下载：72/0  |  提交时间：2021/05/24 aristolochic acid I  glutathione S-transferase placental form-positive foci  clonal expansion  hepatocellular carcinoma  medium-term rat liver bioassay  DNA adducts