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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/04 furmonertinib  autoinduction  food effect  alkaline phosphatase  body weight  pharmacokinetics  modeling and simulation  NSCLC   Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310 作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei 收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01 fungus  Calcarisporium arbuscula  natural product  gene cluster activation  liver fibrosis   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor   Structures of human mGlu2 and mGlu7 homo- and heterodimers 期刊论文 NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+ 作者:  Du, Juan;  Wang, Dejian;  Fan, Hongcheng;  Xu, Chanjuan;  Tai, Linhua 收藏  |  浏览/下载：26/0  |  提交时间：2021/08/17 Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18 作者:  Lan, Xiao-fang;  Olaleye, Olajide E.;  Lu, Jun-lan;  Yang, Wei;  Du, Fei-fei 收藏  |  浏览/下载：75/0  |  提交时间：2021/06/11 LianhuaQingwen  glycyrrhetic acid  24-hydroxyglycyrrhetic acid  Gancao-induced pseudoaldosteronism  licorice-induced pseudoaldosteronism  11β  -hydroxysteroid dehydrogenase 2  COVID-19  colonic microbiota   A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158, 页码: 9 作者:  Huang, Jun-Shang;  Guo, Bin-Bin;  Lin, Fei-Fei;  Zeng, Li-Min;  Wang, Ting 收藏  |  浏览/下载：43/0  |  提交时间：2021/05/24 DGAT1  Inhibitor  Pharmacokinetics  Dyslipidemia  Lipid metabolism   SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 SL010110  gluconeogenesis  primary mouse hepatocytes  PEPCK1  acetylation  degradation   PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文 THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403 作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning 收藏  |  浏览/下载：130/0  |  提交时间：2021/05/24 clear cell renal cell carcinoma  protein arginine methyltransferase 1  therapeutic  lipocalin2 (LCN2)  sunitinib