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浏览/检索结果: 共103条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：31/0  |  提交时间：2022/01/18 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Enones as Alkenyl Reagents via Ligand-Promoted C-C Bond Activation 期刊论文 ACS CATALYSIS, 2021, 页码: 82-88 作者:  Li, Hanyuan;  Wang, Mei-Ling;  Liu, Yu-Wen;  Li, Ling-Jun;  Xu, Hui 收藏  |  浏览/下载：44/0  |  提交时间：2022/01/18 C-C bond activation  enone  olefination  Pd-catalyzed  late-stage diversification   Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue 收藏  |  浏览/下载：21/0  |  提交时间：2022/01/18 Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng 收藏  |  浏览/下载：52/0  |  提交时间：2022/01/18 New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18 I-2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines 期刊论文 GREEN CHEMISTRY, 2021, 卷号: 23, 期号: 22, 页码: 9165-9171 作者:  Wei, Xiaohui;  Liang, Xuewu;  Li, Yazhou;  Liu, Qi;  Liu, Xuyi 收藏  |  浏览/下载：20/0  |  提交时间：2021/12/16 Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 21, 页码: 15217-15227 作者:  Li, Jian;  Li, Hui;  Fang, Daqing;  Liu, Lingjun;  Han, Xu 收藏  |  浏览/下载：17/0  |  提交时间：2022/01/04