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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong 收藏  |  浏览/下载：73/0  |  提交时间：2022/01/04 idiopathic pulmonary fibrosis  DDRs  kinase inhibitor  indazole derivatives  XBLJ-13  nintedanib  bleomycin-induced pulmonary fibrosismouse model   Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Concise synthesis of N-phosphorylated amides through three-component reactions 期刊论文 GREEN CHEMISTRY, 2021, 页码: 5 作者:  Zhu, Yuan-Yuan;  Zhang, Tao;  Zhou, Linlin;  Yang, Shang-Dong 收藏  |  浏览/下载：14/0  |  提交时间：2021/12/16 BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14 作者:  Feng, Mei;  Wu, Zhongen;  Zhou, Yan;  Wei, Zhuang;  Tian, Enming 收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04 Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文 ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893 作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna 收藏  |  浏览/下载：59/0  |  提交时间：2021/11/04 OZ439 (artefenomel)  malaria  metabolite identification  cytochrome P450 metabolism  cytochrome P450 inhibition  time-dependent inhibition   GPR160 is a potential biomarker associated with prostate cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 3 作者:  Guo, Wanjing;  Zhang, Junyu;  Zhou, Yan;  Zhou, Caihong;  Yang, Yunjie 收藏  |  浏览/下载：16/0  |  提交时间：2021/08/17 Cinnacetals A and B: Two highly oxidated and modified isoryanodane diterpenoids from Cinnamomum cassia 期刊论文 TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 5 作者:  Huang, Yi-Qi;  Zhou, Bin;  Yuan, Yu-Rong;  Ren, Yu-Hao;  Li, Dong-Li 收藏  |  浏览/下载：11/0  |  提交时间：2021/08/17 Cinnamomum cassia  Isoryanodane diterpenoid  X-ray crystallography  ECD calculation  Biosynthetic pathway   Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes 期刊论文 NATURE METHODS, 2021, 页码: 29 作者:  Xu, Chunlong;  Zhou, Yingsi;  Xiao, Qingquan;  He, Bingbing;  Geng, Guannan 收藏  |  浏览/下载：28/0  |  提交时间：2021/06/11 (-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 10 作者:  Yan, Bing-Chao;  Zhou, Min;  Li, Jian;  Li, Xiao-Nian;  He, Shi-Jun 收藏  |  浏览/下载：56/0  |  提交时间：2021/05/24 bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation   SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming 收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24 PI3Kδ  PI3K  AKT  mTOR  diffuse large B-cell lymphoma  resistance  combination therapy