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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
发表日期
2020 [11]
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共11条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2020, 卷号: 11, 页码: 13
作者:
Duan, Ya-Nan
;
Ge, Xiang
;
Jiang, Hao-Wen
;
Zhang, Hong-Jie
;
Zhao, Yu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
diphyllin
obesity
brown adipocyte
differentiation
thermogenesis
V-ATPase
SARS-CoV-2 and Three Related Coronaviruses Utilize Multipke ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig
期刊论文
JOURNAL OF VIROLOGY, 2020, 卷号: 94, 期号: 22, 页码: 14
作者:
Li, Yujun
;
Wang, Haimin
;
Tang, Xiaojuan
;
Fang, Shisong
;
Ma, Danting
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
ACE2
ACE2-Ig
SARS-CoV-2
entry inhibitor
host range
Tumor-Activated Size-Enlargeable Bioinspired Lipoproteins Access Cancer Cells in Tumor to Elicit Anti-Tumor Immune Responses
期刊论文
ADVANCED MATERIALS, 2020, 页码: 11
作者:
Li, Jie
;
Wang, Hong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
anti-tumor immune responses
cancer immunotherapy
lipoproteins
oxaliplatin
tumor targeting
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8
Orally delivered legumain-activated nanovehicles improve tumor accumulation and penetration for combinational photothermal- chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 323, 页码: 59-70
作者:
Wang, Jing
;
Wang, Yuqi
;
Cao, Haiqiang
;
Wang, Hong
;
Li, Jie
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/24
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
;
Niu, Ao
;
Li, Yuanqing
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
EGFR(C797S) mutant
SARs
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine
Clinical resistance
Fourth-generation inhibitors
Nanoparticles-mediated reoxygenation strategy relieves tumor hypoxia for enhanced cancer therapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 319, 页码: 25-45
作者:
Wang, Hong
;
Li, Jie
;
Wang, Yuqi
;
Gong, Xiang
;
Xu, Xiaoxuan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Tumor hypoxia
Nanoparticles
Oxygen
Cancer therapy
Apoferritin nanocages loading mertansine enable effective eradiation of cancer stem-like cells in vitro (vol 553, pg 201, 2018)
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 576, 页码: 2
作者:
Tan, Tao
;
Wang, Yuqi
;
Wang, Hong
;
Cao, Haiqiang
;
Wang, Zhiwan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
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