QQ客服 官方微博 反馈留言

浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Further new complex daphniphyllum alkaloids from the stems and leaves of Daphniphyllum calycinum: Structure and stereochemistry 期刊论文 TETRAHEDRON, 2020, 卷号: 76, 期号: 49, 页码: 8 作者:  Shen, Shou-Mao;  Li, Heng;  Wang, Jian-Rong;  Zeng, Yan-Bo;  Guo, Yue-Wei 收藏  |  浏览/下载：19/0  |  提交时间：2020/12/24 Daphniphyllum calycinum  Daphniphyllum alkaloids  Absolute configuration   DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文 BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69 作者:  Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/21 Alzheimer'sdisease  Microglia  AMPK alpha 1  DW14006  Phagocytosis  Neuro-inflammation   Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice 期刊论文 ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56 作者:  Xu, Xiaoju;  Xu, Xu;  Hao, Yanping;  Zhu, Xialin;  Lu, Jian 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 SOMCL-863, a novel, selective and orally bioavailable small-molecule c-Met inhibitor, exhibits antitumor activity both in vitro and in vivo (vol 351, pg 413, 2014) 期刊论文 CANCER LETTERS, 2020, 卷号: 486, 页码: 71-72 作者:  Wang, Lu;  Ai, Jing;  Shen, Yanyan;  Zhang, Haotian;  Peng, Xia 收藏  |  浏览/下载：10/0  |  提交时间：2020/12/24 Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Su, Hai-xia;  Yao, Sheng;  Zhao, Wen-feng;  Li, Min-jun;  Liu, Jia 收藏  |  浏览/下载：115/0  |  提交时间：2020/12/24 SARS-CoV-2  3CL protease  traditional Chinese medicines  Shuanghuanglian oral liquid  baicalin  baicalein   Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856 作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu 收藏  |  浏览/下载：237/0  |  提交时间：2020/12/24 Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)  hepatic steatosis  insulin resistance  caspase-1  interleukin 18 (IL-18)  fatty liver  metabolic disorder  inflammation  cytokine signaling  caspase 1 (CASP1)  tyrosine-protein phosphatase (tyrosine phosphatase)  macrophage   A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction 期刊论文 INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713 作者:  Damaneh, Mohammadali Soleimani;  Hu, Jian-Ping;  Huan, Xia-Juan;  Song, Shan-Shan;  Tian, Chang-Qing 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 BET inhibitor  Cell proliferation  Apoptosis  Anti-cancer agent   Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666 作者:  Li, Xiaokang;  Lu, Jian;  Xu, Yixiang;  Wang, Jiaying;  Qiu, Xiaoxia 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 Alzheimer's disease  Autophagy  Nitazoxanide  beta-amyloid  Tau protein   Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models. 期刊论文 CANCER IMMUNOLOGY RESEARCH, 2020, 卷号: 8, 期号: 3, 页码: 70-70 作者:  Dai, Yang;  Ji, Yichun;  Shen, Yanyan;  Su, Yi;  Liu, Bo 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01