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科研机构
上海药物研究所 [56]
内容类型
期刊论文 [56]
发表日期
2020 [56]
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共56条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2020, 卷号: 11, 页码: 13
作者:
Duan, Ya-Nan
;
Ge, Xiang
;
Jiang, Hao-Wen
;
Zhang, Hong-Jie
;
Zhao, Yu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
diphyllin
obesity
brown adipocyte
differentiation
thermogenesis
V-ATPase
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor
期刊论文
CELL RESEARCH, 2020, 页码: 11
作者:
Sun, Wen
;
Chen, Li-Nan
;
Zhou, Qingtong
;
Zhao, Li-Hua
;
Yang, Dehua
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/12/24
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Teratopyrones A-C, Dimeric Naphtho-gamma-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 21, 页码: 10
作者:
Xu, Ya-Ming
;
Arnold, A. Elizabeth
;
U'Ren, Jana M.
;
Xuan, Li-Jiang
;
Wang, Wen-Qiong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
endophytic fungus
Teratosphaeria
teratopyrones
naphtho-γ
-pyrones
nigerasperone A
Structural basis for activation of the growth hormone-releasing hormone receptor
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:
Zhou, Fulai
;
Zhang, Huibing
;
Cong, Zhaotong
;
Zhao, Li-Hua
;
Zhou, Qingtong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
Tan, Xiaoqin
;
Jiang, Xiangrui
;
He, Yang
;
Zhong, Feisheng
;
Li, Xutong
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:
Xie, Zhifu
;
Jiang, Haowen
;
Liu, Wei
;
Zhang, Xinwen
;
Chen, Dakai
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/21
Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Li, Bo-han
;
Zhang, Mei
;
Duan, Ya-nan
;
Shuai, Lin
;
Jiang, Hao-wen
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/21
AMP-activated protein kinase
pyrazolone derivative C29
obesity
energy expenditure
thermogenesis
inguinal white adipose tissue
white adipose browning
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
期刊论文
CANCER CELL, 2020, 卷号: 38, 期号: 3, 页码: 350-+
作者:
Yuan, Huairui
;
Han, Ying
;
Wang, Xuege
;
Li, Ni
;
Liu, Qiuli
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/24
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