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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文 CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280 作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong 收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24 SPOP  Protein‐  protein interaction  Clear cell Renal Cell Carcinomas  Crystal structure  Peptide inhibitor   Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo 收藏  |  浏览/下载：75/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 13 作者:  Guo, An-Di;  Wei, Dan;  Nie, Hui-Jun;  Hu, Hao;  Peng, Chengyuan 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice 期刊论文 ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56 作者:  Xu, Xiaoju;  Xu, Xu;  Hao, Yanping;  Zhu, Xialin;  Lu, Jian 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi 收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Alleviation of Synovial Inflammation of Juanbi-Tang on Collagen-Induced Arthritis and TNF-Tg Mice Model (vol 11, 45, 2020) 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 2 作者:  Wang, Tengteng;  Jia, Qingyun;  Chen, Tao;  Yin, Hao;  Tian, Xiaoting 收藏  |  浏览/下载：38/0  |  提交时间：2020/12/24 Juanbi-Tang  rheumatoid arthritis  collagen-induced arthritis  synoviocyte  tumor necrosis factor   Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Yu, Yan-yan;  Cui, Shi-chao;  Zheng, Tian-nan;  Ma, Hai-jian;  Xie, Zhi-fu 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 insulin resistance  sarsasapogenin  adipose tissue inflammation  macrophage-adipocyte crosstalk  IKK/NF-kappa B  JNK   A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry 期刊论文 RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11 作者:  Fu, Huan;  Zhang, Qing-li;  Huang, Xiao-wu;  Ma, Zheng-hua;  Zheng, Xiao-li 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen 收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry 期刊论文 BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15 作者:  Liu, Huan;  Sun, Zhaolin;  Tian, Xiaoting;  Feng, Qin;  Guo, Ziqiong 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 HPLC-Q-TOF  intestinal bacteria  liver  metabolism  Qushi Huayu Fang