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浏览/检索结果: 共82条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A novel salviadione derivative, compound 15a, attenuates diabetes-induced renal injury by inhibiting NF-kappa B-mediated inflammatory responses 期刊论文 TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 409, 页码: 11 作者:  Li, Li;  Ding, Chunyong;  Zou, Chunpeng;  Xiong, Zhi;  Zhu, Weiwei 收藏  |  浏览/下载：98/0  |  提交时间：2021/05/24 Salviadione derivative 15a  Diabetic nephropathy  Inflammation  Macrophage infiltration  Fibrosis  Nuclear factor-kappa B  Cytokines   Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文 CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24 作者:  Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang 收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun 收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者:  Ding, Chunyong;  Song, Zilan;  Shen, Ancheng;  Chen, Tingting;  Zhang, Ao 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Immunotherapy  Anti-tumor  cGAS  STING  TBK1  Small molecule modulators   Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Nostoc sphaeroids Kutz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 1734-1742 作者:  Li, Meixia;  Guo, Ciliang;  Wang, Yeqing;  Du, Zhenyun;  Chen, Sheng 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 Nostoc sphaeroids Kutz polysaccharide  Nostoc sphaeroids Kutz powder  16S ribosomal RNA gene sequencing  Core bacterial community   A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115 作者:  Bian, Youcheng;  Zeng, Hui;  Tao, Hong;  Huang, Lulin;  Du, Zhenyun 收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24 Polygala tenuifolia  Pectin  Pancreatic cancer  Apoptosis  Autophagy   A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 161, 页码: 35-43 作者:  Zeng, Hui;  Li, Piaopiao;  Zhou, Lishuang;  Ding, Kan 收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21 Polygala tenuifolia  Pectin  Polysaccharide  A beta(42) Alzheimer's disease   Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses Kras-mutated non-small cell lung cancer 期刊论文 MOLECULAR CANCER RESEARCH, 2020, 卷号: 18, 期号: 10, 页码: 44-45 作者:  Wang, Yu-xiang;  Li, Xian;  Liu, Xue-ling;  Wang, Bo-bo;  Chen, Yi 收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01