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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
发表日期
2020 [25]
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发表日期:2020
专题:上海药物研究所
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Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 13
作者:
Guo, An-Di
;
Wei, Dan
;
Nie, Hui-Jun
;
Hu, Hao
;
Peng, Chengyuan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013
作者:
Chai, Xianzhi
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Supramolecular Assembly of TPE-Based Glycoclusters with Dicyanomethylene-4H-pyran (DM) Fluorescent Probes Improve Their Properties for Peroxynitrite Sensing and Cell Imaging
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2020, 页码: 9
作者:
Dong, Lei
;
Fu, Mengqi
;
Liu, Lifang
;
Han, Hai-Hao
;
Zang, Yi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/21
cell imaging
glycoclusters
peroxynitrite detection
self-assembly
tetraphenylethylene
Structurally diverse halosesquiterpenoids from the red alga Laurencia composita Yamada
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Hu, Zhi-Biao
;
Yu, Xiao-Qing
;
Wang, Bin
;
Liu, Ai-Hong
;
Zhao, Tian-Sheng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Laurencia composita
Chamigrane sesquiterpenoids
Bisabolane sesquiterpenoids
Nerolidol derivative
Modified Mosher's method
Antifungal activity
Antibacterial activity
Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 32, 页码: 8567-8571
作者:
Weber, Maria
;
Han, Hai-Hao
;
Li, Bo-Han
;
Odyniec, Maria L.
;
Jarman, Charlotte E. F.
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  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
Structural basis of GPBAR activation and bile acid recognition
期刊论文
NATURE, 2020, 页码: 29
作者:
Yang, Fan
;
Mao, Chunyou
;
Guo, Lulu
;
Lin, Jingyu
;
Ming, Qianqian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/24
A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11
作者:
Fu, Huan
;
Zhang, Qing-li
;
Huang, Xiao-wu
;
Ma, Zheng-hua
;
Zheng, Xiao-li
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Highly selective monitoring of in-source fragmentation sapogenin product ions in positive mode enabling group-target ginsenosides profiling and simultaneous identification of seven Panax herbal medicines
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2020, 卷号: 1618, 页码: 11
作者:
Zhang, Chun-xia
;
Wang, Xiao-yan
;
Lin, Zhao-zhou
;
Wang, Hong-da
;
Qian, Yue-xin
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/01
In-source fragmentation
Ginsenoside
Selective ion monitoring
Characteristic chromatogram
Panax
Traditional Chinese medicine formula
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