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科研机构
上海药物研究所 [8]
内容类型
期刊论文 [8]
发表日期
2020 [8]
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发表日期:2020
专题:上海药物研究所
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Recent Progress in the Design and Application of Supramolecular Peptide Hydrogels in Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2020, 页码: 23
作者:
Cai, Ying
;
Zheng, Chao
;
Xiong, Fengqin
;
Ran, Wei
;
Zhai, Yihui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/21
cancer
hydrogels
local therapy
peptides
supramolecular self-assembly
Recent Progress in the Design and Application of Supramolecular Peptide Hydrogels in Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2020, 页码: 23
作者:
Cai, Ying
;
Zheng, Chao
;
Xiong, Fengqin
;
Ran, Wei
;
Zhai, Yihui
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/21
cancer
hydrogels
local therapy
peptides
supramolecular self-assembly
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11
作者:
Fu, Huan
;
Zhang, Qing-li
;
Huang, Xiao-wu
;
Ma, Zheng-hua
;
Zheng, Xiao-li
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
The role of critical micellization concentration in efficacy and toxicity of supramolecular polymers
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 9, 页码: 4518-4526
作者:
Su, Hao
;
Wang, Feihu
;
Ran, Wei
;
Zhang, Weijie
;
Dai, Wenbing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
critical micellization concentration
molecular assembly
supramolecular polymers
drug delivery
prodrugs
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