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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812 作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan 收藏  |  浏览/下载：235/0  |  提交时间：2019/01/08 IDH1 inhibitor  Imidazole cyclopropyl amine  Structure-based rational design   Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography 期刊论文 PHYTOCHEMICAL ANALYSIS, 2018, 卷号: 29, 期号: 6, 页码: 639-648 作者:  Ma, Yaqian;  Liu, Menghan;  Tan, Ting;  Yan, Aiping;  Guo, Lan 收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08 Box-Behnken design  Camellia oleifera flowers  deep eutectic solvents  flavonoids  response surface methodology   Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 4, 页码: 587-596 作者:  Zheng, Yue-ming;  Wang, Wan-fu;  Li, Yan-fen;  Yu, Yong;  Gao, Zhao-bing 收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 Nav1.7 channels  analgesics  CNV1014802  inactivated state  paroxysmal extreme pain disorder   Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153 作者:  Zha, Chuantao;  Deng, Wenjia;  Fu, Yan;  Tang, Shuai;  Lan, Xiaojing 收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08 Structure-based drug design  Selective CDK4/6 inhibitors  Structure-activity relationship study  In vivo antitumor activity