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复旦大学上海医学院 [13]
中国医学科学院 北京... [8]
上海药物研究所 [7]
西安交通大学 [5]
四川大学 [2]
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期刊论文 [50]
发表日期
2017 [50]
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LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Wang, Yi-yang
;
Xu, Xin
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
LX2343
cognitive deficits
oxidative stress
tauopathy
mitochondria
GSK-3 beta inhibitor
neuroprotection
ICV-STZ rats
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway
期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:
Zhou, Ting-Ting
;
Ma, Fei
;
Shi, Xiao-Fan
;
Xu, Xin
;
Du, Te
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Gaq signaling
hepatic gluconeogenesis
protein kinase B (AKT)
type 2 diabetes mellitus (T2DM)
Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047
作者:
Yang, Zhong-min
;
Liao, Xue-mei
;
Chen, Yi
;
Shen, Yan-yan
;
Yang, Xin-ying
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
homologous recombination repair defects
breast cancer
ovarian cancer
TALEN
combined biomarker
simmiparib
olaparib
Evolution of the Asian summer monsoon during Dansgaard/Oeschger events 13-17 recorded in a stalagmite constrained by high-precision chronology from southwest China
期刊论文
QUATERNARY RESEARCH, 2017, 卷号: 88, 期号: 1, 页码: 121-128
作者:
Li, Ting-Yong
;
Han, Li-Yin
;
Cheng, Hai
;
Edwards, R. Lawrence
;
Shen, Chuan-Chou
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/06/17
Asian Summer Monsoon
Stalagmite Delta O-18
Th-230 Dating
Dansgaard/oeschger Events
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560
作者:
Sun, Jing-ya
;
Wang, Ji-dong
;
Wang, Xin
;
Liu, Hong-chun
;
Zhang, Min-min
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
Stalagmite-inferred centennial variability of the Asian summer monsoon in southwest China between 58 and 791 ka BP
期刊论文
QUATERNARY SCIENCE REVIEWS, 2017, 卷号: 160, 期号: 2017, 页码: 1-12
作者:
Shen, Chuan-Chou
;
Spoetl, Christoph
;
Cheng, Hai
;
Zhao, Xin
;
Huang, Chun-Xia
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2018/10/17
Stalagmite Delta O-18
Asian Summer Monsoon
Greenland Interstadials
Heinrich Event 6
Southern Hemisphere
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials
期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:
Yuan, Bo
;
Ye, Na
;
Song, Shan-Shan
;
Wang, Yu-Ting
;
Song, Zilan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Homologous recombination repair defects
Olaparib
Growth inhibition
Patient-derived xenografts
Pharmacokinetics
Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 4, 页码: 3330-3342
作者:
Li, Li-Ming
;
Han, Min
;
Jiang, Xin-Chi
;
Yin, Xian-Zhen
;
Chen, Fu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
hyaluronic acid
hydrogel scaffold
mesenchymal stem cells
adhesive peptide
spinal cord injury
tissue engineering
Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168
作者:
He, Jin-Xue
;
Wang, Meng
;
Huan, Xia-Juan
;
Chen, Chuan-Huizi
;
Song, Shan-Shan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
MPH
PARP inhibitor
homologous recombination
antitumor activity
synthetic lethality
Allergy march of Chinese children with infantile allergic symptoms: a prospective multi-center study
期刊论文
WORLD JOURNAL OF PEDIATRICS, 2017, 卷号: 13, 期号: 4
作者:
Gao, Qi
;
Ren, Yi-Xin
;
Liu, Yong-Ge
;
Ma, Lin
;
Gu, Xiao-Hong
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
allergic rhinitis
allergy march
asthma
atopic dermatitis
infant
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