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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2017     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel diaryltriazines with a picolinonitrile moiety as potent HIV-1 RT inhibitors: a patent evaluation of WO2016059647(A2) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 1, 页码: 9-15 作者:  Huang, Boshi;  Zhou, Zhongxia;  Kang, Dongwei;  Li, Wanzhuo;  Chen, Zihui 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/16 Diaryltriazine  HIV-1 RT inhibitors  picolinonitrile  modeling  simulation  highly conserved residues   Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 190-201 作者:  Li, Xiao;  Gao, Ping;  Huang, Boshi;  Zhou, Zhongxia;  Yu, Zhao 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 HIV  NNRTIs  Indolylarylsulfones  Antiviral activity  SAR  Molecular  modeling  Chemical space  Drug design   Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 16, 页码: 4397-4406 作者:  Huang, Boshi;  Wang, Xueshun;  Liu, Xinhao;  Chen, Zihui;  Li, Wanzhuo 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 HIV-1 inhibitors  DAPY-IAS hybrids  Crystallographic overlays  Drug  design  SARs  Molecular modeling   Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives as potent HIV-1 NNRTIs 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 383-391 作者:  Liu, Zhaoqiang;  Tian, Ye;  Liu, Jinghan;  Huang, Boshi;  Kang, Dongwei 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/12 HlV-1  NNRTIs  Pyridine  Bioisosteric principle  Drug design   Inhibitors of Influenza Virus Polymerase Acidic (PA) Endonuclease: Contemporary Developments and Perspectives 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 9, 页码: 3533-3551 作者:  Ju, Han;  Zhang, Jian;  Huang, Boshi;  Kang, Dongwei;  Huang, Bing 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/12 The development of an effective synthetic route of lesinurad (RDEA594) 期刊论文 CHEMISTRY CENTRAL JOURNAL, 2017, 卷号: 11 作者:  Meng, Qing;  Zhao, Tong;  Kang, Dongwei;  Huang, Boshi;  Zhan, Peng 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/12 Lesinurad  Uric acid salt transport protein 1  Gout  Synthesis   Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 10, 页码: 4424-4443 作者:  Kang, Dongwei;  Fang, Zengjun;  Huang, Boshi;  Lu, Xueyi;  Zhang, Heng 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/12