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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157 作者:  Wang, Wen-Long;  Chen, Xiao-Yu;  Gao, Ya;  Gao, Li-Xin;  Sheng, Li 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Benzo[c][1,2,5] thiadiazole derivatives  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan 期刊论文 CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 8, 页码: 1711-1715 作者:  Wu, Zheng-Feng;  Bao, Han;  Zhou, Fa-Yang;  Liu, Jing-Xin;  Meng, Fan-Cheng 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Caesalpinia sappan  Cassane diterpenoid  Phanginin  Caesalsappanin  Cytotoxicity   Synthesis of MeON-neoglycosides of digoxigenin with 6-deoxy- and 2,6-dideoxy-D-glucose derivatives and their anticancer activity 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15, 页码: 3359-3364 作者:  Wang, Dong-dong;  Li, Xiao-san;  Bao, Yu-zhou;  Liu, Jie;  Zhang, Xiao-kun 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Digoxigenin  MeON-glycosylation  Deoxy-sugar  Anticancer  Nur77 nuclear receptor   LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119 作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Wang, Yi-yang;  Xu, Xin 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Alzheimer's disease  LX2343  cognitive deficits  oxidative stress  tauopathy  mitochondria  GSK-3 beta inhibitor  neuroprotection  ICV-STZ rats   DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文 JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169 作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Gaq signaling  hepatic gluconeogenesis  protein kinase B (AKT)  type 2 diabetes mellitus (T2DM)   The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABA(A) Receptor Endocytosis in the vmPFC 期刊论文 JOURNAL OF NEUROSCIENCE, 2017, 卷号: 37, 期号: 30, 页码: 7096-7110 作者:  Wang, Weisheng;  Ju, Yun-Yue;  Zhou, Qi-Xin;  Tang, Jian-Xin;  Li, Meng 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 aversive memory  drug withdrawal  endocytosis  extinction  GABA(A) receptor  Rac1   CimicifoetonesA and B, Dimeric Prenylindole Alkaloids as Black Pigments of Cimicifuga foetida 期刊论文 CHEMISTRY-AN ASIAN JOURNAL, 2017, 卷号: 12, 期号: 12, 页码: 1277-1281 作者:  Zhou, Chang-Xin;  Yu, Yu-E;  Sheng, Rong;  Mo, Jian-Xia;  Huang, Min 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 alkaloids  apoptosis  cimicifoetones  cytotoxicity  natural products  structure elucidation   Deficiency of the G protein G alpha q ameliorates experimental autoimmune encephalomyelitis with impaired DC-derived IL-6 production and Th17 differentiation 期刊论文 CELLULAR & MOLECULAR IMMUNOLOGY, 2017, 卷号: 14, 期号: 6, 页码: 557-567 作者:  Lai, Weiming;  Cai, Yingying;  Zhou, Jinfeng;  Chen, Shuai;  Qin, Chaoyan 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Dendritic cells  EAE  G alpha q  IL-6  Th17 differentiation  MS   Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases 期刊论文 PROTEIN SCIENCE, 2017, 卷号: 26, 期号: 4, 页码: 834-846 作者:  Chen, Yan-Na;  Gu, Xin;  Zhou, X. Edward;  Wang, Weidong;  Cheng, Dandan 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 shark  Sus  TBC1D15  GAP  crystal structure  GTPase activity assay   Discovery of BVDU as a promising Drug for autoimmune diseases Therapy by Dendritic-cell-based functional screening 期刊论文 SCIENTIFIC REPORTS, 2017, 卷号: 7 作者:  Chen, Shuai;  Zhou, Jinfeng;  Cai, Yingying;  Zheng, Xinyuan;  Xie, Sirong 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08