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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2016     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Right-handed and left-handed G-quadruplexes have the same DNA sequence: distinct conformations induced by an organic small molecule and potassium 期刊论文 CHEMICAL COMMUNICATIONS, 2016, 卷号: 52, 期号: 65, 页码: 10052-10055 作者:  Fu, Boshi;  Huang, Jinguo;  Chen, Yuqi;  Wang, Yafen;  Xue, Tianrui 收藏  |  浏览/下载：19/0  |  提交时间：2016/11/04 Discovery of bioactive molecules from CuAAC click-chemistry-based combinatorial libraries 期刊论文 DRUG DISCOVERY TODAY, 2016, 卷号: 21, 期号: 1, 页码: 118-132 作者:  Wang, Xueshun;  Huang, Boshi;  Liu, Xinyong;  Zhan, Peng 收藏  |  浏览/下载：1/0  |  提交时间：2019/12/16 Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 352-363 作者:  Chen, Wenmin;  Zhan, Peng;  Daelemans, Dirk;  Yang, Jiapei;  Huang, Boshi 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16 Piperidyl  Morpholinyl  Pyridine  Diarylpyrimidines  NNRTI  HIV   Novel diarylpyrimidines and diaryltriazines as potent HIV-1 NNRTIs with dramatically improved solubility: a patent evaluation of US20140378443A1 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 2, 页码: 281-289 作者:  Huang, Boshi;  Kang, Dongwei;  Yang, Jiapei;  Zhan, Peng;  Liu, Xinyong 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16 HIV-1 inhibitors  diarylpyrimidine  Aqueous solubility  diaryltriazine  NNRTI  drug design   Discovery of non-peptide small molecular CXCR4 antagonists as anti-HIV agents: Recent advances and future opportunities 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 114, 页码: 65-78 作者:  Zhang, Heng;  Kang, Dongwei;  Huang, Boshi;  Liu, Na;  Zhao, Fabao 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16 AIDS  HIV-1  CXCR4  Small molecular  Entry inhibitors  Drug design   Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 3, 页码: 380-385 作者:  Li, Wenxin;  Huang, Boshi;  Kang, Dongwei;  De Clercq, Erik;  Daelemans, Dirk 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/16 anti-HIV-1 activity  drug design  HIV-1  NNRTIs  S-DABOs   An improved synthesis approach of the HIV-1 inhibitor RDEA427, a pyrrolo[2,3-d]pyrimidine derivative 期刊论文 ARKIVOC, 2016, 页码: 45-51 作者:  Huang, Boshi;  Liu, Xinhao;  Li, Wanzhuo;  Chen, Zihui;  Kang, Dongwei 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/17 HIV-1 inhibitor  RDEA427  diarylpyrimidine-like derivative  increased  overall yield  environment-friendly   Design, Synthesis, and Biological Evaluation of Novel 2-(Pyridin-3-yloxy)acetamide Derivatives as Potential Anti-HIV-1 Agents 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 87, 期号: 2, 页码: 283-289 作者:  Huang, Boshi;  Li, Xiao;  Zhan, Peng;  De Clercq, Erik;  Daelemans, Dirk 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/17 anti-HIV activity  bioisosterism  HIV-1 RT  molecular hybridization  non-nucleoside reverse transcriptase inhibitors   Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 109, 页码: 294-304 作者:  Yang, Jiapei;  Chen, Wenmin;  Kang, Dongwei;  Lu, Xueyi;  Li, Xiao 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17 HIV-1  NNRTIs  DAPY  Molecular hybridization  Drug design  Entrance  channel   Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 18, 页码: 4424-4433 作者:  Lu, Xueyi;  Li, Xiao;  Yang, Jiapei;  Huang, Boshi;  Kang, Dongwei 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17 HIV-1  AIDS  NNRTIs  Purinylthioacetanilide  Anti-HIV activity  Drug  design  Bioisosterism