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浏览/检索结果: 共24条，第1-10条 帮助 限定条件 专题：合肥物质科学研究院    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 An overview of kinase downregulators and recent advances in discovery approaches 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6 作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25 Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors 期刊论文 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, 卷号: 35 作者:  Li, Xia;  Ni, Maowei;  Xu, Xiaoling;  Chen, Wei 收藏  |  浏览/下载：21/0  |  提交时间：2020/11/30 Glutathione reductase  isothiocyanate  inhibitor  thiocarbamoylation   Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627 作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang 收藏  |  浏览/下载：32/0  |  提交时间：2019/08/23 Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557 作者:  Wang, Beilei;  Deng, Yuanxin;  Chen, Yongfei;  Yu, Kailin;  Wang, Aoli 收藏  |  浏览/下载：39/0  |  提交时间：2018/08/16 Btk  Kinase Inhibitor  Irreversible Inhibitor  Structure-activity Relationship  B-cell Lymphoma   Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl) phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 131, 页码: 107-125 作者:  Liang, Qianmao;  Chen, Yongfei;  Yu, Kailin;  Chen, Cheng;  Zhang, Shouxiang 收藏  |  浏览/下载：37/0  |  提交时间：2018/07/26 Btk  Irreversible Inhibitor  Kinase Inhibitor  Structure-activity Relationship  B-cell Lymphoma   Determining Cysteines Available for Covalent Inhibition Across the Human Kinome 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2879-2889 作者:  Zhao, Zheng;  Liu, Qingsong;  Bliven, Spencer;  Xie, Lei;  Bourne, Philip E. 收藏  |  浏览/下载：13/0  |  提交时间：2018/07/26 Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962 作者:  Wang, Aoli;  Li, Xixiang;  Wu, Hong;  Zou, Fengming;  Yan, Xiao-E 收藏  |  浏览/下载：34/0  |  提交时间：2018/07/26 Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962 作者:  Wang, Aoli;  Li, Xixiang;  Wu, Hong;  Zou, Fengming;  Yan, Xiao-E 收藏  |  浏览/下载：41/0  |  提交时间：2018/07/26 Determining Cysteines Available for Covalent Inhibition Across the Human Kinome 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2879-2889 作者:  Zhao, Zheng;  Liu, Qingsong;  Bliven, Spencer;  Xie, Lei;  Bourne, Philip E. 收藏  |  浏览/下载：13/0  |  提交时间：2018/07/26 Determining Cysteines Available for Covalent Inhibition Across the Human Kinome 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2879-2889 作者:  Zhao, Zheng;  Liu, Qingsong;  Bliven, Spencer;  Xie, Lei;  Bourne, Philip E. 收藏  |  浏览/下载：11/0  |  提交时间：2018/07/26