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科研机构
中国医学科学院 北京... [8]
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期刊论文 [6]
会议论文 [2]
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2019 [1]
2018 [1]
2017 [1]
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专题:中国医学科学院 北京协和医学院
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Pharmacokinetics, excretion and metabolites analysis of DL0410, a dual‑acting cholinesterase inhibitor and histamine‑3 receptor antagonist
期刊论文
2019, 卷号: 20, 期号: 2, 页码: 1103-1112
作者:
Pang Xiaocong
;
Zhao Ying
;
Song Junke
;
Kang De
;
Wu Song
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids
期刊论文
2018, 卷号: 148, 页码: 238-254
作者:
Li, Guoliang
;
Hong, Ge
;
Li, Xinyu
;
Zhang, Yan
;
Xu, Zengping
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Tacrine
Alzheimer's disease
Cholinesterase inhibitors
A beta aggregation
Neuroprotection
Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer's Disease Agents Using Pharmacophore, 3D-QSAR and Molecular Docking Approaches
期刊论文
2017, 卷号: 22, 期号: 8
作者:
Pang, Xiaocong
;
Fu, Hui
;
Yang, Shilun
;
Wang, Lin
;
Liu, Ai-Lin
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/04
cholinesterase inhibitor
Alzheimer's disease
DL0410
3D-QSAR
molecular docking
kinetics
Cholinesterase and Human Lung Cancer Cells (A-549) Inhibitory Activity of the Cassava Peel of Euphorbiaceae in Vitro
会议论文
Joint International Conference on Social Science and Environmental Science (SSES) / International Conference on Food Science and Engineering (ICFSE ), Guangzhou, PEOPLES R CHINA
作者:
Chen, Xiao-Ming
;
Zhang, Zhi-Jun
;
Liu, Ai-Lin
;
Lv, Fei-Jie
;
Li, Shu-Fang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Cassava Peel
Extraction
AchE
BuChE
Inhibitory Activity
Anti-tumor
A-549
Cholinesterase and Human Lung Cancer Cells (A-549) Inhibitory Activity of the Cassava Peel of Euphorbiaceae in Vitro
会议论文
JOINT 2016 INTERNATIONAL CONFERENCE ON SOCIAL SCIENCE AND ENVIRONMENTAL SCIENCE (SSES 2016) AND INTERNATIONAL CONFERENCE ON FOOD SCIENCE AND ENGINEERING (ICFSE 2016), 2016-01-01
作者:
Chen, Xiao-Ming
;
Zhang, Zhi-Jun
;
Liu, Ai-Lin
;
Lv, Fei-Jie
;
Li, Shu-Fang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/04
Cassava Peel
Extraction
AchE
BuChE
Inhibitory Activity
Anti-tumor
A-549
DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against A beta-induced neuronal damage via the Akt/JNK signaling pathway
期刊论文
2016, 卷号: 37, 期号: 11, 页码: 1401-1412
作者:
Zhou, Dan
;
Zhou, Wei
;
Song, Jun-ke
;
Feng, Zhang-ying
;
Yang, Ran-yao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Alzheimer's disease
amyloid beta-peptides
cholinesterase inhibitor
DL0410
learning and memory
CREB/BDNF
Akt/JNK
neuroprotection
DL0410 can reverse cognitive impairment, synaptic loss and reduce plaque load in APP/PS1 transgenic mice
期刊论文
2015, 卷号: 139, 期号: Pt A, 页码: 15-26
作者:
Yang, Ran-Yao
;
Zhao, Gang
;
Wang, Dong-Mei
;
Pang, Xiao-Cong
;
Wang, Shou-Bao
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  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
DL0410
Alzheimer's disease
Amyloid beta
Senile plaque
Synapse
Cholinesterase inhibitor
The Effects of Galangin on a Mouse Model of Vitiligo Induced by Hydroquinone
期刊论文
2014, 卷号: 28, 期号: 10, 页码: 1533-1538
作者:
Huo, Shi-Xia
;
Liu, Xin-Ming
;
Ge, Chun-Hui
;
Gao, Li
;
Peng, Xiao-Ming
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
galangin
vitiligo
mouse
hydroquinone
melanin
melanocytes
cholinesterase
tyrosinase
malondialdehyde
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