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科研机构
山东大学 [16]
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期刊论文 [16]
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2019 [1]
2018 [1]
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专题:山东大学
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Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3836-3845
作者:
Gao, Ping
;
Cheng, Xiqiang
;
Sun, Lin
;
Song, Shu
;
Alvarez, Mar
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV-1
RNase H
Integrase
Dual inhibitors
5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 155, 页码: 714-724
作者:
Sun, Lin
;
Gao, Ping
;
Dong, Guanyu
;
Zhang, Xujie
;
Cheng, Xiqiang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
HAART
HIV-1 dual inhibitors
HIV-1 IN
RNase H
5-hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives
Privileged
structure
Identification of spirocyclic or phosphate substituted quinolizine derivatives as novel HIV-1 integrase inhibitors: a patent evaluation of WO2016094197A1, WO2016094198A1 and WO2016154527A1
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 11, 页码: 1277-1286
作者:
Cheng, Xiqiang
;
Gao, Ping
;
Sun, Lin
;
Tian, Ye
;
Zhan, Peng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/12
AIDS
HIV-1
IN inhibitors
prodrug
privileged structure
drug design
1-Hydroxypyrido[2,3-d]pyrimidin-2(1H)-ones as novel selective HIV integrase inhibitors obtained via privileged substructure-based compound libraries
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 20, 页码: 5779-5789
作者:
Gao, Ping
;
Zhang, Lingzi
;
Sun, Lin
;
Huang, Tianguang
;
Tan, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/12
HIV-1
CuAAC
HIV-1 integrase
HIV-1 RNase H
"Privileged
structure"-guided scaffold reposition
Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase
期刊论文
Bioorganic and medicinal chemistry, 2014, 卷号: 22, 期号: 19, 页码: 5446-5453
作者:
Zhang, Daoguang
;
Debnath, Bikash
;
Yu, Shenghui
;
Sanchez, Tino Wilson
;
Christ, Frauke
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
HIV-1 integrase inhibitors
INSTIs
5-Hydroxy-6-oxo-1
6-dihydropyrimidine analogues
Docking-based CoMFA and CoMSIA study of azaindole carboxylic acid derivatives as promising HIV-1 integrase inhibitors
期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2013, 卷号: 24, 期号: 10, 页码: 819-839
作者:
Yu, S.
;
Wang, P.
;
Li, Y.
;
Liu, Y.
;
Zhao, G.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
3D-QSAR
docking
CoMFA
CoMSIA
HIV-1 integrase inhibitors
azaindole
carboxylic acid derivatives
Design and synthesis of novel pyrimidone analogues as HIV-1 integrase inhibitors
期刊论文
Bioorganic and Medicinal Chemistry Letters, 2013, 卷号: 23, 期号: 22, 页码: 6134-6137
作者:
Yu,S.
;
Sanchez,T.W.
;
Liu,Y.
;
Yin,Y.
;
Neamati,N.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
HIV-1
Integrase inhibitors
Pyrimidone analogues
Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2012, 卷号: 27, 期号: 5, 页码: 628-640
作者:
Yu, Shenghui
;
Zhang, Linna
;
Yan, Shifeng
;
Wang, Peng
;
Sanchez, Tino
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
HIV-1
integrase inhibitors
polyhydroxylated aromatics
structure-activity relationship
Development of Polyphenols as HIV-1 Integrase Inhibitors: a Summary and Perspective
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2012, 卷号: 19, 期号: 32, 页码: 5536-5561
作者:
Yu, S.
;
Zhao, G.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
AIDS
HIV-1
integrase
inhibitors
mechanism
drug resistance
polyphenols
1,5-DCQA
SAR
computer-aided drug design
evolution
perspective
[Advances in the study of HIV-1 integrase inhibitors of alpha, gamma-diketo compounds].
期刊论文
Yao xue xue bao = Acta pharmaceutica Sinica, 2010, 卷号: 45, 期号: 2
作者:
Yu, Sheng-hui
;
Tan, Yan-mei
;
Zhao, Gui-sen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/26
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