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科研机构
上海药物研究所 [18]
内容类型
期刊论文 [16]
会议论文 [2]
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2021 [1]
2019 [1]
2016 [2]
2014 [3]
2013 [2]
2011 [3]
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Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Diao, Xingxing
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
novel psychoactive substances
NPS
synthetic cannabinoid
SC
metabolism
urinary metabolites
hepatocyte incubation
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines
会议论文
作者:
Ren J(任进)
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  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines
Effects of Renal Impairment on the Pharmacokinetics of Morinidazole: Uptake Transporter-Mediated Renal Clearance of the Conjugated Metabolites
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 卷号: 58, 期号: 7, 页码: 4153-4161
作者:
Zhong, Kan
;
Li, Xiuli
;
Xie, Cen
;
Zhang, Yifan
;
Zhong, Dafang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Cordyceps sinensis protects against liver and heart injuries in a rat model of chronic kidney disease: a metabolomic analysis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 697-706
作者:
Liu, Xia
;
Zhong, Fang
;
Tang, Xu-long
;
Lian, Fu-lin
;
Zhou, Qiao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Cordyceps sinensis
chronic kidney disease
liver injury
heart injury
metabolomics
nuclear magnetic resonance
traditional Chinese medicine
Quantitative analysis of theophylline and its metabolites in urine of Chinese healthy subjects after oral administration of theophylline sustained-release tablets
期刊论文
Acta Pharmaceutica Sinica, 2014, 卷号: 49, 期号: 7, 页码: 1039-1043
作者:
Liu Ying
;
Zhan Yan
;
Zhang Yifan
;
Chen Xiaoyan
;
Zhong Dafang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
LC-HESI/MS/MS
LC-HESI/MS/MS
theophylline
1, 3-dimethyluric acid
3-methylxanthine
1-methyluric acid
Combinatorial Metabolism Notably Affects Human Systemic Exposure to Ginsenosides from Orally Administered Extract of Panax notoginseng Roots (Sanqi)
期刊论文
DRUG METABOLISM AND DISPOSITION, 2013, 卷号: 41, 期号: 7, 页码: 1457-1469
作者:
Hu, Zheyi
;
Yang, Junling
;
Cheng, Chen
;
Huang, Yuhong
;
Du, Feifei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
期刊论文
DRUG METABOLISM AND DISPOSITION, 2013, 卷号: 41, 期号: 2, 页码: 430-444
作者:
Diao, Xingxing
;
Deng, Pan
;
Xie, Cen
;
Li, Xiuli
;
Zhong, Dafang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 卷号: 879, 期号: 1, 页码: 69-74
作者:
Wang, Donggeng
;
Zhang, Zhiwen
;
Ju, Jianfeng
;
Wang, Xinyang
;
Qiu, Wenjing
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Piceid
HPLC-MS-MS
In vitro metabolism
Urinary metabolite
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