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科研机构
上海药物研究所 [33]
内容类型
期刊论文 [33]
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2021 [1]
2019 [2]
2018 [2]
2017 [4]
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2014 [5]
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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007
作者:
Trevarton, Alexander J.
;
Zhou, Yan
;
Yang, Dehua
;
Rewcastle, Gordon W.
;
Flanagan, Jack U.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Cancer
YB-1
Luciferase
AlphaScreen
Transcription factor
Single-stranded DNA
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor
High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 6, 页码: 889-899
作者:
Yuliantie, Elita
;
Dai, Xinchuan
;
Yang, Dehua
;
Crack, Peter J.
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
High-throughput screening
Interferon alpha receptor
Secreted embryonic alka-line phosphatase
JAK-STAT
IFN regulatory factor
Inhibitor
highthroughputscreeningforsmallmoleculeinhibitorsofthetypeiinterferonsignalingpathway
期刊论文
actapharmaceuticasinicab, 2018, 卷号: 000, 期号: 006, 页码: 889
作者:
Yuliantie Elita
;
Dai Xinchuan
;
Yang Dehua
;
Crack Peter J
;
Wang Mingwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
High-throughput
screening
Interferon
α
receptor
Secreted
embryonic
alkaline
phosphatase
JAK-STAT
IFN
regulatory
factor
Inhibitor
γ-Secretase Epsilon-cleavage Assay
期刊论文
Bio-protocol, 2017, 卷号: 7, 期号: 22
作者:
Xu, Ting-Hai
;
Yan, Yan
;
Harikumar, Kaleeckal G
;
Miller, Laurence J
;
Melcher, Karsten
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Detection of Membrane Protein Interactions by Cell-based Tango Assays
期刊论文
Bio-protocol, 2017, 卷号: 7, 期号: 22
作者:
Yan, Yan
;
Xu, Ting-Hai
;
Harikumar, Kaleeckal G
;
Miller, Laurence J
;
Melcher, Karsten
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1 alpha Promoter Activity
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 5, 页码: 1428-1435
作者:
Niu, Biao
;
Ke, Chang-Qiang
;
Li, Bo-Han
;
Li, Yuanyuan
;
Yi, Yongji
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Establishment of a reporter gene system for activity detection of hepatocyte nuclear factor 4alpha
期刊论文
Academic Journal of Second Military Medical University, 2017, 卷号: 38, 期号: 9, 页码: 1112-1118
作者:
Sun Bingjie
;
Chen Shijie
;
Deng Longfei
;
Ding Chenhong
;
Chen Fei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Ninjurin 1
hepatocyte nuclear factor 4alpha
Ninjurin 1
reporter gene system
small molecular compound
Inhibitory effects of vina-ginsenoside R7 on activation of rat C6 astrocytes induced by LPS and TNF-α combination
期刊论文
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, 卷号: 41, 期号: 8, 页码: 1498-1503
作者:
Wang, Xiao-Shuang
;
Huang, Tao
;
Qin, Li-Yue
;
Li, Hong-Li
;
Lan, Yun-Yi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
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