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Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载:48/0  |  提交时间:2021/05/24
Increasing the Sampling Efficiency of Protein Conformational Change by Combining a Modified Replica Exchange Molecular Dynamics and Normal Mode Analysis 期刊论文
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2021, 卷号: 17, 期号: 1, 页码: 13-28
作者:  Peng, Cheng;  Wang, Jinan;  Shi, Yulong;  Xu, Zhijian;  Zhu, Weiliang
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Li, Bo-han;  Zhang, Mei;  Duan, Ya-nan;  Shuai, Lin;  Jiang, Hao-wen
收藏  |  浏览/下载:53/0  |  提交时间:2020/12/21
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong
收藏  |  浏览/下载:26/0  |  提交时间:2020/12/24
Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate 期刊论文
FASEB JOURNAL, 2020, 页码: 18
作者:  Hait, Nitai C.;  Maiti, Aparna;  Xu, Pan;  Qi, Qianya;  Kawaguchi, Tsutomu
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/01
Isolation and structural characterization of a pectin from Lycium ruthenicum Murr and its anti-pancreatic ductal adenocarcinoma cell activity 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 223, 页码: 10
作者:  Zhang, Shihai;  He, Fei;  Chen, Xia;  Ding, Kan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Natural constituents from food sources: potential therapeutic agents against muscle wasting 期刊论文
FOOD & FUNCTION, 2019, 卷号: 10, 期号: 11, 页码: 6967-6986
作者:  Shen, Shengnan;  Yu, Hua;  Gan, Lishe;  Ye, Yang;  Lin, Ligen
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:  He, Shijun;  Liu, Xing;  Lin, Zemin;  Liu, Yuting;  Gu, Lei
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/01
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min
收藏  |  浏览/下载:44/0  |  提交时间:2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08


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